Antitussives Flashcards
1
Q
Prototype
A
Dextromethorphan
2
Q
Route
A
PO
3
Q
Pharmacokinetics
A
Peak effect 15-30 min
4
Q
Metabolized
A
Liver –> first pass
5
Q
Excreted
A
Kidney
6
Q
Action
A
Depress cough center in medulla
7
Q
Use
A
suppress dry, hacking, nonproductive cough
use during night for productive cough but not during the day
8
Q
Adverse effects
A
Nausea
difficulty breathing
drowsiness
9
Q
Interaction
A
increased chance of serotonin syndrome with
SSRIs
MAOIs
SNRIs
TCAs
