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Patho Pharm > Fibrates > Flashcards

Fibrates Flashcards

1
Q

Prototype

A

Fenofibrate

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2
Q

Route

A

PO

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3
Q

Pharmacokinetics

A

highly protein bound

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4
Q

Metabolized

A

Liver

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5
Q

Excreted

A

Kidneys

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6
Q

Actions

A

inhibits triglyceride synthesis

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7
Q

Use

A

Serum triglycerides greater than 500

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8
Q

Adverse effects

A

GI discomfort
diarrhea
gallstones

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9
Q

Interactions

A

Increased risk of bleeding with Coumadin
Increased risk of myopathy with statins
Decreased effects with bile acid sequestrants

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10
Q

Contraindications

A

liver disease
gallbladder disease
renal disease

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11
Q

Nursing

A

give with food to increase absorption

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Patho Pharm (22 decks)

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