Pathology of SI Flashcards
1
Q
Duodenal Atresia
A
Complete occlusion/end of lumen of the Duodenum
2
Q
Meckels Diverticulum
A
- Persistent vitelline/omphalomesenteric duct -> Ileal outpouching
- Rule of 2s: 2% hav them; 2 fet from Ileocecal valve; Symptomatic before age 2
3
Q
Meconium ileus
A
- Cystic fibrosis -> PAncratic insufficiency -> accumulation of meconium; MAinly in newborns
- S/S: Dark green stool. perforation, perotinitis, volvulus, aspiration, fetal distress
4
Q
SI Bacterial Toxigenic organisms
A
- V. Cholera
- Enterotoxigenic E. Coli (ETEC)
- Enterohemorrhagic E. Coli (EHEC)
- Enteroaggregative E. Coli (EAEC)
- Enteroinvasive E. Coli
- Salmonella
- Shigella
- Yersinia
- Campylobacter
5
Q
SI Viral Pathogens
A
- Norwalk: Upper SDI w/ patchy mucosal lesions + Malabsorption
- Rotavirus: Severe Watery diarrhea in young children
6
Q
Thrombotic Microangiopathic H.U.S.
A
- Shiga Toxin or Shiga-like Toxin
- S/S: Bloody diarrhea, Uremia
- Microthrombotic obliteration of glomerulus
7
Q
Atypical HUS
A
- congenitalDefects in Complement factor H, CD46, or Factor I
- remitting-relapsing course
8
Q
Types of Mechanical obstruction of the bowel
A
- Herniation
- Adhesion (#1 cause)
- Volvulus (twisting)
- intrussusception: Bowel protrudes distally
9
Q
Most common intestinal infarct
A
Superior mesenteric artery -> SI ischemia
10
Q
Angor Abdominalis
A
Pain after eating; sign of bowel ischemia due to atherosclerosis
11
Q
Most common Mesenteric Vein thrombosis
A
Superior mesenteric
12
Q
Causes of Nonocclusive intestinal ischemia
A
Hypoxic shock, hemorrhage, MI, + Pseudomonas
13
Q
Celiac Pathogenesis
A
- Antigliadin Abs; anti-tTG Abs (ATA)
14
Q
Celiac Morph
A
- Blunting/loss of Villi
- Lymphocytic infiltration of crypts + lamina propria
15
Q
Whipple Disease Presentation
A
- White men 30-40 YO
- S/S: arthralgia, diahrrea, weight loss, abdominal pain
