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Gastrointestinal System > Functional Dx of GI Tract > Flashcards

Functional Dx of GI Tract Flashcards

1
Q

Ileus Causes

A
  • Opiates
  • Anticholinergics
  • Infx
  • Kidney failure
  • Diverticulitis
  • MI
  • Hypokalemia
  • Hypercalcemia
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2
Q

Ileus Tx

A

NPO; IV Fluids; NG tube

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3
Q

Meconium Ileus

A
  • Infant Ileus of bile salts, acids, + debris
  • XR: Soap bubbles
  • Tx: Enema, N-Acetylcysteine. Sx
  • A/S: CF
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4
Q

IBS Definition

A

Characterized by chronic or recurrent abdominal pain, bloating, mucus in feces, and an erratic disturbance of defecation without a clearcut etiology.

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5
Q

Rome IV criteria

A

Recurrent abdominal pain at least 1 day/ week with < 2 or more criteria:

  • Related to defecation
  • A/S w/ change in freq of stool
  • A/S w/ change in appearance of stool
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6
Q

Extraabdominal IBS S/S

A

Fatigue, fibromyalgia, sleep disturbance, chronic headache

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7
Q

IBS Red Flags

A
  • Age
  • Fever
  • WL
  • Bleeding
  • Vomiting
  • Hematemesis
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8
Q

IBS Treatment

A
  • Diet modification + avoidance
  • S/S Drug Tx: Hyoscyamine, Lubiprostone, Linaclotide, plecanatide
  • Laxatives: polyethylene glycol
  • Other: Prucalopride (5HT agonist)
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9
Q

IBS-D Tx

A
  • Dipheoxylate
  • Loperamide
  • Rifaximin
  • Alosetron (refractory)
  • Eluxadoline
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10
Q

Eluxadoline Contra

A

Cholecystectomy, sphincter of Oddi Dysfx, Liver Dx, Alchoholism

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11
Q

CD antigens Celiace

A

HLA-DQ2/8

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12
Q

Celiac Workup

A
  • AntiGliadin + Anti-tTG IgA or IgG

- Derm Herpet Skin biopsy

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13
Q

Celiac Tx

A
  • Diet Modification

- Corticosteroids during crisis

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14
Q

Gluten-containing cereals

A

Wheat, Barley, + Rye

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15
Q

Functional Dyspepsia Cause + S/S + Diagnosis

A
  • N/0 infiltration of gastric mucosa
  • Et: NSAIDs, smoking, alcohol, uremia, trauma/burns, shock
  • Diagnose w/ endoscopy
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16
Q

Path H. Pylori

A
  • Induces IL-8 -> N/0 recruitment
  • Production of Urease to buffer HCl
  • Adherence to surface epithelium
  • Production of VacA -> cell injury via CagA gene
17
Q

Differentiating Immune gastritis vs H. Pylori

A
  • Immune is more severe -> Achlorhydria
  • Urease test
  • Culture
  • stool antigen test
  • serologic tests
18
Q

H. Pylori Treatment

A
  • Bismuth salt, metronidazole and amoxicillin (or tetracycline) •Bismuth salt, ranitidine and clarithromycin
  • Amoxicillin, clarithromycin and proton pump inhibitor like omeprazole
19
Q

H/ Pylori Characteristics

A
  • Gram (-) motile rod
  • Microaerophilic
  • Oxidase +, Catalase +, Urease +
  • Cilver stain

Gastrointestinal System (32 decks)

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