Digestion/Absorption Flashcards
alpha amylase
a-1,4 digestion
Glucose/galactose Gut Cell transport
Enter enterocyte via SGLT1 Na+ cotransporter
Exit via Glut2 transporter
How does fructose enter the enterocyte?
GLUT5
SGLT1 Deficiency
- AR disorder
- Diarrhea when consuming Glucose or Galactose; Does not affect fructose
Chief Cells secrete
Pepsinogen
Gastric Lipase
Parietal cells secrete
H+. Cl-. Intrinsic factor
How are Dipeptides absorbed onto enterocytes?
Teriary active cotransport w/ H+
How do amino acids enter + exit enterocytes?
Enter via Na+/Amino acid symporters
Exit via cation-independent transporters
Manifestations of amino acid transporter mutations
Clinically silent; can usually be absorbed via oligopeptides
Steatorrhea
Excessive fat in feces
Bile contents
Bile acids, phosphatidylcholine, + cholesterol (10:3:1)
B12 absorption
Binds IF in stomach, absorbed in ilium
Water absoprtion
- occurs in SI
- most moves passively by transcellularly w/ some paracellular transport which are both mediated by by ion flux
Na+ Absoprtion
- Jejunum
- transcellular by nutrient cotransporters + Basolateral Na/K exchange
what hormone enhances Na+absorption by increasing the activity of both apical ENaC channels and basolateral Na-K pumps
Aldosterone
