Pathology of Renal Tumours Flashcards
What is agenesis?
absence of one or both kidneys
What is hypoplasia?
small kidneys but normal development
What are horseshoe kidneys?
fusion at either pole, usually lower
What is cystic disease?
different from polycystic! simple cysts, very common, usually no functional disease
What is the infantile type of polycystic disease?
ARPKD
In which type of polycystic disease is there distortion of the reniform shape?
ADPKD
What is ARPKD associated with?
congenital hepatic fibrosis
What is the most common form of congenital cystic disease?
ADPKD
Where is the defect in PKD1?
chromosome 16
Where is the defect in PKD2?
chromosome 4
How does ADPKD usually present?
in adult middle life
with abdominal mass, haematuria and hypertension
What type of renal englargement occurs in ADPKD?
MASSIVE
What is ADPKD associated with?
Berry aneurysms in circle of Willis - subarachnoid haemorrhage
Name the common benign tumour which is white and has medullary origin.
fibroma
Describe a renal adenoma.
yellowish, in cortical region
What is an angiomyolipoma?
tumour which is a mix of fat, muscle and blood vessels
What is angiomyolipoma associated with?
tuberous sclerosis
What is JGCT?
tumour with production of renin,
causing secondary hypertension
