Renal Transplantation Flashcards
1
Q
What are the cell surface proteins expressed in cells on cells which activate the immune system if they are non self?
A
HLA (human leucocyte antigen)
2
Q
What are the 3 important types of HLA?
A
A, B and DR
3
Q
What is hyperacute rejection?
A
rejection in a matter of mins due to cross match preformed antibodies - cannot fix this.
4
Q
What is acute rejection?
A
T/B cell mediation. Can fix by increasing immunosuppression
5
Q
What drug type can be used as antirejection therapy?
A
calcineurin inhibitors
6
Q
What may be suitable for type 1 diabetics with kidney disease?
A
kidney pancreas dual transplant
7
Q
What does transplant increase risk of cancer of?
A
skin cancer
