pathology of intracranial tumours Flashcards

1
Q

key concept in intracranial tumours is a raised

A

ICP

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2
Q

causes of raised ICP

A

haemorrhage

tumour

abscess

oedema post trauma

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3
Q

SOL

A

space occupuing lesion

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4
Q

3 examples of a SOL

A

tumour

bleeding (haematoma)

abscess

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5
Q

effects of a SOL

A

amount of tissue increases

raises ICP

causes herniation between the intracranial spaces

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6
Q

uncal herniation

A

cerebrum moves over the edge of tentorium

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7
Q

coning

A

cerebellum moves inferiorly into foramen magnum

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8
Q

cerebellar tonsillar herniation is a major cause of

A

brain stem death

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9
Q

herniation onto the optic nerve gives

A

palpilloedema

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10
Q

as pressure increases what 3 things happen?

A

reduced GCS

pupillary dilatation

brain stem death

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11
Q

what tests would you do for coma without focal signs or meningism?

A

toxicology (alcohol)

blood sugar and electrolytes

assess hepatic function and renal function

acid base measurements

BP

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12
Q

metastatic spread of intracranial tumours is to what sites?

A

breast

lung

kidney

colon

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13
Q

adenoma is a tumour of the

A

pituitary gland

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14
Q

glioma or astrocytoma is a tumour of

A

glial cells

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15
Q

neurofibroma or a schawnnoma is a tumour of

A

nerve sheath cell

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16
Q

astrocytomas are low grade and grow very

A

slowly

17
Q

giloblastomas are malignant astrocytes that grow very

A

quickly

18
Q

meningioma develops from what cells that make up the brain covering?

A

arachnocytes

19
Q

meningioma is a …….. tumour

does not metastasise!

A

benign / slow growing

20
Q

what is an acoustic neuroma?

A

shwannoma of 8th CN

vestibulocochlear