Multiple Sclerosis Flashcards
what is multiple sclerosis?
inflammatory plaques of demyelination in the CNS
what is the peak ago of occurrence of MS?
30
MS is also known as …….. matter disease
white
what crosses the blood brain barrier causing demyelination?
activated T cells
demyelination is an autoimmune process caused by:
2 things
activated T cells crossing the blood brain barrier
acute inflammation of the myelin sheath
myelitis
inflammation of the spinal cord
symptoms of MS
optic neuritis
dysaethesia (swallowing disorder)
pins and needles
trigeminal neuralgia
spastic weakness
myelitis
low mood
tremor
limb weakness
diplopia/vertigo/ataxia
sarcoidosis
collection of lumps of cells causing inflammation and leading to granuloma
a diagnosis can be made of MS by using what two criteria?
macdonald (MRI)
posers (clinical)
What are the three types of MS?
relapsing remitting
secondary progressive
primary progressive
what is the most common type of MS?
relapsing remitting - 85%
primary progressive MS often occurs in your
5th or 6th decade of life
What type of MS has no relapses?
primary progressive
neuromyelitis can be treated with what class of drugs?
immunosuppressants
MS can be treated with injections of……
or orally by….
beta - interferons
dimethyl fumarate
