Patho- SPace occupying lesions Flashcards
What things can cause a space occupying lesion?
Bleeds
Tumour
Idiopathic intracranial hypertension
Hydrocephalus
What types of bleed can cause a space occupying lesion?
Extradural
Subdural
SAH
What can cause an extradural hematoma?
Trauma
What can cause a subdural hematoma?
Ruptured bridging vein
What can cause a SAH?
CoW rupture/Berry aneurysm
What is the most common brain tumour?
Secondary mets
What are the most common mets to the brain?
Breast
Bronchus
Malignant melenoma
What are the two categories of primary brain tumour?
Extrinsic- Meninges
Intrinsic- Brain parenchyma
Give an example of extrinsic brain tumours?
Meningioma
From where does a meningioma normally occur?
Subarachnoid
What are some symptoms of a meningioma?
Largely asymptomatic
Headache
CN neuropathy
Can erode bone
How do you treat a meningioma?
CT/MRI- Homogenous, space-occupying lesion that densely enhances after contrast media
Leave
Surgery
Radio
What is the most common form of intrinsic brain tumour?
Glioma
What kind of cells do glioma arise from?
Glial cells
Can gliomas metastase?
Yes but only to the brain
What glial cells do gliomas tend to arise from?
Astrocytes
Oligoendrocytes
What are the symptoms of an oligodendrocyte glioma?
Slow growing Solid pink/grey Frontal lobe 25-45YO Seizures Can become malignant Calcifications
How do you treat an oligodendrocyte glioma?
Surgery and chemo
What are the four grades of an astrocytoma?
I- Benign
II- Start benign then transform
III/IV- Malignant then die in months
What is an example of a grade I astrocytoma?
Pilocytic astrocytoma
What is a Pilocytic astrocytoma?
Grade I astrocytoma