Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

IC > Part II: Dementia, ADHD, Narcolepsy, NM disorders > Flashcards

Part II: Dementia, ADHD, Narcolepsy, NM disorders Flashcards

1
Q

Loss of cholinergic activity in the hippocampus proposed explanation for

A

loss of cognition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Cholinesterase inhibitor used as cognitive enhancer

A

Tacrine
Donepezil (muscle cramps)
Rivastigmine
Galantamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Non-competitive NMDA antagonist similar to ketamine used in Alzheimers

A

Memantine (usually coadministered w/ AchE inhibitor)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Area of the brain implicated in ADHD pathology

A

dopamine/noradrenergic systems projecting from frontosubcortical brain regions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Narcolepsy is associated w/ decreased expression of ______ in the brain

A

Orexin (hypocretin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drugs for ADHD/Narcolepsy

A

Methylphenidate
Dexymethylphenidate
d-Amphetamine
Lisdexamfetamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Norepinephrine and dopmine re-uptake inhibitor that increases glutamatergic activity and decreases GABAergic activity to treat ADHD/Narcolepsy

A

Modafenil
Armodafinil

both class IV drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Non stimulants to treat ADHD

A

Atomoxetine

Gaunfecine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

anti-spastic

A 
Diazepam
Baclofen (GABA-B agonist, intrathecal)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

alpha 2 adrenergic agonist used as an anti-spastic

A

Tizanidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Drug that acts on muscles that decrease Ca2+ release from the SR

A

Dantrolene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Drug that inhibits Ach release from vesicles in muscle used as an antispastic

A

Botulinum toxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Drugs used for the acute treatment of muscle spasm

A

cyclobenzaprine
Carisoprodol
Ophenadrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

IC (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions