Parkinson's

Question 1

What are the 3 Parkinson’s drugs used to alleviate symptoms?

Answer 1

1. Bromocriptine
2. levodopa
3. carbidopa

Question 2

How do these drugs work?

Answer 2

1. increase dopamine levels

2. block cholinergic transmission

Question 3

What it the physiological cause of parkinsons?

Answer 3

damage to the dopaminergic neurons so they release less dopamine

Question 4

What is the effect of less dopamine?

Answer 4

There is more Ach activity

Question 5

What are the 2 nuerotransmitters that help regulate normal acitivty of nerves that control voluntary skeletal muscle movement?

Answer 5

1. Dopamine

2. Ach

Question 6

What does dopamine do?

Answer 6

Inhibit activity and decrease muscle tone

Question 7

What does Ach do?

Answer 7

excitatory stimulation and increase muscle tone

Question 8

What are the symptoms of Parkinsons?

Answer 8

1. bradykinesia
2. rigidity
3. abnormal reflexes
4. tremors at rest
5. drooling

Question 9

Which drug is an anticholinergic?

Answer 9

Bromocriptine

Question 10

What is the MOA of levodopa and carbidopa?

Answer 10

inhibit reuptake of dopamine