Anti-emetics Flashcards
1
Q
What is an anti-emetic drug used for?
A
- nausea
- vomiting
- motion sickness
- vertigo
2
Q
Stimulation of what receptors can cause nausea/vomiting?
A
D2 receptors
3
Q
What are the 2 treatment goals of emesis?
A
- remove sensation - nausea
2. remove vomiting
4
Q
What is the general MOA of anti-emetics?
A
Block D2 and Serotonin receptors in the CTZ zone
5
Q
What is the CTZ?
A
Chemoreceptor Trigger Zone
6
Q
Where is the CTZ found?
A
Medulla - which modulates some forms of nausea and vomiting
7
Q
What other drugs can block emesis?
A
Histamine blockers - like bendaryl
8
Q
What are the 4 antiemetic drugs to know?
A
- Prochlorperazine
- Diphenhydramine/Benadryl
- Scopolamine (also an anticholinergic used for intestinal disorders)
- Dimenhydrinate/Dramamine
