Parasitology - Lecture 7 Flashcards
Describe the general features of the superfamily Filaroidea
- long, thin and slender
- anterior and posterior are simple
- eggs contain larvae or microfilariae
- locate in blood and lymph nodes, body cavities, CT, etc.
- indirect lifecycles (IH = arthropods)
What 2 families are under the superfamily Filarioidea?
- Filariidae
- Onchocercidae
What is the general feature of he family Filariidae?
locate in skin/ subcut tissue, cause skin lesions that attract IH to take eggs and larvae
What is a common name for the pathology caused by Parafilarioa multipapillosa?
‘bloody sweat’ or ‘summer bleeding’
what species and where does Parafilaria multipapillosa infect?
coiled in nodules in subcut and muscular CT of horses
describe the morphology of Parafilaria multipapillosa
large number of papilliform thickening at anterior end
describe the lifecycle of Parafilaria multipapillosa
IH = fly
- skin nodules open and blood containing eggs or larvae flows onto skin of host
- IH ingests eggs, L3 develops in IH, infected flies transfer L3 when they feed again.
- disease appears in spring/ summer and disappears in winter. will reoccur annually for 3-4 years before resolving
What species and where does Parafilaria bovicola infect?
- subcut and intermuscular CT in cattle
What species and where does Stephanofilaria spp. infect? how is it transmitted?
skin of cattle. transmitted by buffalo fly
What is the significance of Dirofilaria immitis to humans?
can infect humans, but wont mature
describe the morphology of Dirofilaria immitis
- elongated, filiform worms, females 25-30cm long
- circular mouth with no lips
- female (viviparous) vulva located near anterior end
- male posterior end is curled
What species and where does Dirofilaria immitis locate in the host?
dogs, cats, humans
- adults in pulmonary artery, right ventricle, right atrium. caudal vena cava in heacy infections
- microfilaria in blood
describe the features of microfilaria
- found in blood
- on blood smear with anticoagulant: show nonprogressive motility
- have a tapering cephalic end and a straight caudal end
decribe the lifecycle fo Dirofilaria immitis
IH = mosquitoes
- microfilariae mature to L3 in mosquito after infection by taking a blood meal
- L3 migrate to head and mouth parts of mosquito and pass into DH on next feed via puncture wound.
- PPT = 6-9 months
- Dirofilaria immitis host intracellular bacteria, “Wolbachia pipientis”. essential for survival and reproduction of worms, so this is target of control of worms
What species and where does Onchocerca cervicalis infect?
funicular portion of nuchal ligament of horses
describe the morphology of Onchocerca cervicalis
- white, filariform, striated cuticle with spiral thickening
- vulva located anteriorly, unequal spicules
- have microfilaria
What pathology is caused by Onchocerca cervicalis?
hypersensitivity reaction to microfilaria cn cause alopecia, scaling, crusting, lichenification, etc.