Papulosquamous Disorders

Question 1

Psoriasis definition

Answer 1

Chronic, inflammatory skin condition

Question 2

Psoriasis age

Answer 2

Can be seen at any age, peak diagnosis in early 20s and middle age

Question 3

Psoriasis morphologies

Answer 3

Plaque, guttate, inverse/flexural, generalized/erythrodermic, pustular, acral/palmoplantar, Auspitz sign, nail pitting

Question 4

Psoriasis histology

Answer 4

Regular acanthosis, hyperkeratosis, parakeratosis with neutrophils and diminished granular layer, thinning of supra papillary plate with dilated capillaries

Question 5

Psoriasis topical treatments

Answer 5

Corticosteroids, calcipotriene, retinoids, coal tar, calcineurin inhibitors

Question 6

Psoriasis systemic treatments

Answer 6

Phototherapy, retinoids, immunomodulators, biologics

Question 7

Psoriasis associated diseases

Answer 7

Psoriatic arthritis and increased risk of cardiovascular disease

Question 8

Atopic dermatitis defintion

Answer 8

Chronic, inflammatory skin condition

Question 9

Atopic dermatitis age

Answer 9

Typically diagnosed in infancy/early childhood

Question 10

Atopic dermatitis morphology

Answer 10

Pruritus, papulosquamous eruptions on knees, elbows, forehead and cheeks of infant, more acral locations in children (neck, groin, elbows, wrist, ankles, back of knee, eyes, forehead)

Question 11

Atopic dermatitis histology

Answer 11

Spongiosis, edema, parakaratosis, hyperplasia

Question 12

Atopic dermatitis associated diseases

Answer 12

Food allergy, atopic rhinitis, asthma, AKA atopic march

Question 13

Atopic dermatitis treatment

Answer 13

Gentle skin care/barrier, anti-inflammatories, addressing the itch-rash cycle, preventing triggers

Question 14

Contact dermatitis definition

Answer 14

Inflammatory reaction caused by an externally applied substance

Question 15

Contact dermatitis - allergy cause

Answer 15

Contact with substance causes a delayed hypersensitivity reaction, previous exposure necessary

Question 16

Contact dermatitis - irritant cause

Answer 16

Contact with substance causes immediate reaction, no previous exposure necessary, typically dosage dependent

Question 17

Allergic contact dermatitis morphology

Answer 17

Pruritus, erythema, scale, vesicles or bullae, distributed in sites of exposure

Question 18

Allergic contact dermatitis common causes

Answer 18

Poison ivy/poison oak, nickel, fragrance, neomycin

Question 19

Allergic contact dermatitis histology

Answer 19

Spongiosis, lymphocytes and eosinophils in dermis, surface exudate, upper dermal edema

Question 20

Allergic contact dermatitis evaluation

Answer 20

Patch testing

Question 21

Allergic contact dermatitis treatment

Answer 21

Avoidance, topical steroids, oral steroids, gentle skin care/emollients

Question 22

Lichen planus morphology

Answer 22

Pruritic, purple, polygonal, planar papules (5 Ps), Wickham’s striae, koebnerizes, affects scalp, nails, genitals

Question 23

Lichen planus histology

Answer 23

Band-like lymphocytic infiltrate along dermal epidermal junction with saw-tooth rete ridges

Question 24

Lichen planus associated diseases

Answer 24

Hepatitis C, possibly metal dental work

Question 25

Lichen planus treatment

Answer 25

Topical steroids, antihistamines

Question 26

Lichen planus oral involvement

Answer 26

Wickham’s striae, erosions or ulcers, higher risk for oral cancer

Question 27

Pityriasis rosea definition

Answer 27

Acute exanthem

Question 28

Pityriasis rosea age

Answer 28

Younger people

Question 29

Pityriasis rosea morphology

Answer 29

Starts with herald patch, then monomorphic eruption of papule in relaxed tension lines (Christmas tree pattern)

Question 30

Pityriasis rosea histology

Answer 30

Parakeratosis, spongiosis, mild lymphocytic exocytosis, red cell extravasation, superficial perivascular infiltrate, regular acanthosis