Pain and Inflammation/1

Question 1

inflammation chemical mediators

3

Answer 1

1. bradykinins
2. histamines
3. prostaglandins

Question 2

adrenal gland - inflammation

Answer 2

excretes cortisol

Question 3

uricosurics function

Answer 3

decrease uric acid levels

Question 4

types of analgesics

2

Answer 4

NSAIDs

opioids

Question 5

NSAIDS function

Answer 5

interfere with production of prostaglandins

Question 6

types of anti-inflammatories

2

Answer 6

glucocorticoids

uricosurics

Question 7

3 cats of drugs that support the tx of pain

Answer 7

1. nonopioid analgesics
2. opioid analgesics
3. opioid antagonists

Question 8

4 types of nonopioid analgesics that tx pain

Answer 8

1. 1st gen nonsteriod NSAIDs - COX1 and 2 inhibitors
2. 2nd gen NSAIDS COX2
3. tylenol
4. centrally-acting nonopioids

Question 9

NSAIDS - COX1/2 inhibitors therap uses

5

Answer 9

1. inflammation suppression
2. analgesia to mild-mod pain
3. fever reduction
4. dysmenorrhea
5. inhibition of plt aggregation (aspirin)

Question 10

NSAID types

5

Answer 10

1. asa
2. ibuprofen
3. naproxen
4. indomethacin
5. ketorolac

Question 11

naproxen is to

Answer 11

nsaid

Question 12

indomethacin is to

Answer 12

nsaid

Question 13

ketorolac is to

Answer 13

nsaid

Question 14

nsaid a/e

9

Answer 14

1. gastric upset
2. heartburn
3. nausea
4. gastric ulcer
5. bleeding
6. kidney issues
7. salicylism (asa)
8. reye’s syndrome (asa)
9. thromboembolic events

Question 15

sign of salicylism from ASA

Answer 15

tinnitus

Question 16

nsaid COX 2 inhibitor rx ex

1

Answer 16

celecoxib

Question 17

celecoxib is to

Answer 17

nsaid - cox2 inhibitor

Question 18

nsaid - cox2 inhibitor s/e

6

Answer 18

1. diarrhea
2. nausea
3. gastric ulcer
4. heartburn
5. renal dysfunction
6. cardiov. and cerebrov events

Question 19

acetaminophen s/e

2

Answer 19

1. liver damage

2. htn

Question 20

acetaminophen early signs of OD/poisoning

5

Answer 20

1. abd discomfort
2. nausea
3. vomiting
4. sweating
5. diarrhea

Question 21

counteract OD from tylenol

Answer 21

acetylcysteine

Question 22

tylenol - max dose a day

Answer 22

3 G

Question 23

centrally acting nonopioids 1 ex

Answer 23

tramadol

Question 24

tramadol s/e

9

Answer 24

1. sedation
2. dizziness
3. headache
4. nausea
5. vomiting
6. constipation
7. respiratory depression
8. seizure
9. urinary retention

Question 25

opioid agonists therap. uses

2

Answer 25

1. analgesia for mod to severe pain

2. preoperative sedation and reduction of anxiety

Question 26

opioid agonists rx examples

7

Answer 26

1. morphine
2. fentanyl
3. meperidine
4. methadone
5. codeine
6. oxy
7. hydrocodone

Question 27

meperidine is to

Answer 27

opioid agonist

Question 28

morphine is to

Answer 28

opioid agonist

Question 29

codeine, oxy is to

Answer 29

opioid agonist

Question 30

opioid agonists pharm action

Answer 30

mimics actions of naturally occurring opioids - endorphins, enkephalins

Question 31

opioid agonists s/e

10

Answer 31

1. respiratory depression
2. sedation
3. dizziness
4. lightheadedness
5. drowsiness
6. constipation
7. NV
8. OH
9. urinary retention
10. cough suppression

Question 32

opioid agonists - for RR < 12bpm do what

Answer 32

withhold drug, stimulate breathing, and administer an opioid antagonist if indicated

Question 33

opioid agonists contraindications

5

Answer 33

1. pregnant
2. kidney failure
3. increase ICP
4. biliary colic or surgery
5. preterm labor