Book Ch. 33 Flashcards

1
Q

methotrexate complications

5

A
  1. increased risk of infection
  2. hepatic fibrosis and toxicity
  3. BMS
  4. ulcerative stomatitis/GI ulcer
  5. fetal death/congenital abnorm.
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2
Q

hydroxychloroquine complications

1

A
  1. retinal damage/blindness
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3
Q

adalimumab is administered what route

A

sub q

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4
Q

a/e - rhabdo

A

colchicine - gout antiinflammatory

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5
Q

DMARDs

2

A
  1. methotrexate

2. hydroxychloroquine

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6
Q

retinal damage

A

hydroxychloroquine

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7
Q

gluco. for gout

A

prednisone

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8
Q

milnacipran

A

snri - fibrom.

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9
Q

duloxetine

A

snri - fibrom.

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10
Q

nsaids for gout

3

A
  1. indomethacin
  2. naproxen
  3. diclofenac
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11
Q

DMARDs therap. uses

5

A
  1. analgesia for pain, swelling, and joint stiffness
  2. maintenance of joint function
  3. slow/delay the worsening of the disease
  4. prevent organ rejection
  5. manage IBD
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12
Q

give with folic acid to reduce GI and hepatic toxicity

A

methotrexate

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13
Q

cyclosporine complications

5

A
  1. risk of infection
  2. hepatotoxicity/jaundice
  3. nephrotoxicity
  4. hirsutism
  5. gingival hyperplasia
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14
Q

antigout antiinflamm. agent

1

A

colchicine

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15
Q

a/e to monitor for - allopurinol

3

A
  1. nausea
  2. rash
  3. increased gout pain
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16
Q

etanercept med. administration

3

A
  1. sq injection 2/day
  2. monitor site for infection
  3. rotate sites
17
Q

inhibit uric acid production

A

allopurinol

18
Q

belimumab tx

A

sle

19
Q

colchicine complications

4

A
  1. mild GI distress
  2. BMS
  3. thrombocytopenia
  4. rhabdo
20
Q

a/e of etanercept

4

A
  1. severe infections
  2. HF
  3. severe skin reaction - steven johnson syndrome
  4. hematologic disorders
21
Q

antimalarial agent is to

A

hydroxychloroquine

22
Q

med for fibromy. - SNRI

2

A

duloxetine

milnacipran

23
Q

colchicine is to

A

only effective for inflammation caused by gout

24
Q

gold salts is to

A

auranofin

25
Q

belimumab complications

6

A
  1. GI effects
  2. headache
  3. depressed mood
  4. insomnia
  5. infusion reaction
  6. increased risk of infection
26
Q

a/e - gingival hyperplasia, hirsutism

A

cyclosporine

27
Q

etanercept therap. uses

A

DMARD classified as a tumor necrosis factor antagonists - suppresses manifestations of mod to severe RA

28
Q

tumor necrosis factor antagonists

2

A
  1. etanercept

2. infliximab

29
Q

auranofin complications

5

A
  1. toxicity - pruritis, rashes, stomatitis
  2. renal toxicity - proteinuria
  3. blood dyscrasias
  4. hepatitis
  5. GI upset
30
Q

allopurinol complications

5

A
  1. hypersensitivity reaction
  2. kidney injury
  3. hepatitis
  4. GI distress
  5. increase in gout attacks - during 1st month of tx.
31
Q

agents for hyperuricemia

3

A
  1. allopurinol
  2. febuxostat
  3. probenecid
32
Q

DMARDs pharm action

3

A
  1. slow joint degnerations and progression of RA
  2. relief of inflammation and pain
  3. delay disease progression
33
Q

med for SLE

A

belimumab