Book Ch. 33 Flashcards
methotrexate complications
5
- increased risk of infection
- hepatic fibrosis and toxicity
- BMS
- ulcerative stomatitis/GI ulcer
- fetal death/congenital abnorm.
hydroxychloroquine complications
1
- retinal damage/blindness
adalimumab is administered what route
sub q
a/e - rhabdo
colchicine - gout antiinflammatory
DMARDs
2
- methotrexate
2. hydroxychloroquine
retinal damage
hydroxychloroquine
gluco. for gout
prednisone
milnacipran
snri - fibrom.
duloxetine
snri - fibrom.
nsaids for gout
3
- indomethacin
- naproxen
- diclofenac
DMARDs therap. uses
5
- analgesia for pain, swelling, and joint stiffness
- maintenance of joint function
- slow/delay the worsening of the disease
- prevent organ rejection
- manage IBD
give with folic acid to reduce GI and hepatic toxicity
methotrexate
cyclosporine complications
5
- risk of infection
- hepatotoxicity/jaundice
- nephrotoxicity
- hirsutism
- gingival hyperplasia
antigout antiinflamm. agent
1
colchicine
a/e to monitor for - allopurinol
3
- nausea
- rash
- increased gout pain
etanercept med. administration
3
- sq injection 2/day
- monitor site for infection
- rotate sites
inhibit uric acid production
allopurinol
belimumab tx
sle
colchicine complications
4
- mild GI distress
- BMS
- thrombocytopenia
- rhabdo
a/e of etanercept
4
- severe infections
- HF
- severe skin reaction - steven johnson syndrome
- hematologic disorders
antimalarial agent is to
hydroxychloroquine
med for fibromy. - SNRI
2
duloxetine
milnacipran
colchicine is to
only effective for inflammation caused by gout
gold salts is to
auranofin
belimumab complications
6
- GI effects
- headache
- depressed mood
- insomnia
- infusion reaction
- increased risk of infection
a/e - gingival hyperplasia, hirsutism
cyclosporine
etanercept therap. uses
DMARD classified as a tumor necrosis factor antagonists - suppresses manifestations of mod to severe RA
tumor necrosis factor antagonists
2
- etanercept
2. infliximab
auranofin complications
5
- toxicity - pruritis, rashes, stomatitis
- renal toxicity - proteinuria
- blood dyscrasias
- hepatitis
- GI upset
allopurinol complications
5
- hypersensitivity reaction
- kidney injury
- hepatitis
- GI distress
- increase in gout attacks - during 1st month of tx.
agents for hyperuricemia
3
- allopurinol
- febuxostat
- probenecid
DMARDs pharm action
3
- slow joint degnerations and progression of RA
- relief of inflammation and pain
- delay disease progression
med for SLE
belimumab