Book Ch. 47

Question 1

amphotericin B and K

Answer 1

can cause hypokalemia

Question 2

hepatotoxicity s/s

5

Answer 2

1. anorexia
2. malaise
3. fatigue
4. nausea
5. yellow skin/eyes

Question 3

rifampin and bleeding

Answer 3

can increase bleeding if taken with warfarin - monitor pt/inr

Question 4

isoniazid complications

3

Answer 4

1. peripheral neuropathy
2. hepatotoxicity
3. hyperglycemia

Question 5

isoniazid is contraindicated for clients who

1

Answer 5

1. have liver disease

Question 6

a/e of isoniazid

3

Answer 6

1. paresthesias
2. hepatotoxicity
3. hyperglycemia

Question 7

4 drugs that tx tb

Answer 7

RIPE -
isoniazid
rifapentide
pyrazinamide
ethambutol

Question 8

pretreat with diphenhydramine and acetaminophen with what drug

Answer 8

amphotericin B

Question 9

amphotericin B complications

5

Answer 9

1. infusion reaction
2. thrombophlebitis
3. nephrotoxic
4. electrolyte imbalances
5. BMS

Question 10

metronidazole and pregnancy

Answer 10

cat B - but contraindicated during lactation

Question 11

antifungals and kidney

Answer 11

contraindicated in kidney disease

Question 12

isoniazid peripheral neuropathy s/s and results from

Answer 12

tingling, numbness, burning, pain; from def of pyridoxine (vitamin B6)

Question 13

med of choice for parasitic infections

Answer 13

metronidazole

Question 14

antiprotozoal prototype

Answer 14

metronidazole

Question 15

which TB med can cause pseudo. colitis

Answer 15

rifampin

Question 16

rifampin complications

Answer 16

1. discoloration of body fluids
2. hepatotoxicity
3. mild GI upset
4. pseudomembranous colitis

Question 17

2 antifungal prototypes

Answer 17

amphoteriricn B

ketoconazole

Question 18

rifampin and HIV meds

Answer 18

increased dosage of HIV meds are often necessary

Question 19

monitor what during isoniazid

Answer 19

liver function

Question 20

TB drugs - avoid consumption of what and why

Answer 20

alcohol - bc TB drugs are hepatotoxic

Question 21

metronidazole complications

6

Answer 21

1. GI - NV
2. dry mouth
3. metallic taste
4. darkened urine
5. neurotoxicity - numbness, ataxia, seizures
6. p. colitis

Question 22

ketoconazole complications

2

Answer 22

1. hepatotoxicity

2. effects on sex hormones

Question 23

metronidazole is to

Answer 23

anti parasitic

Question 24

metronidazole contraindication

3

Answer 24

1. active CNS disorders (can cause seizures)
2. blood dyscrasias
3. lactation

Question 25

amphotericin B infusion reaction s/s

4

Answer 25

1. fever
2. chills
3. rigors
4. headache 1-3 hour after start