Pain Flashcards
per year how much prescription in USA
$470 billion
over the counter price
35$ per year (no prescription needed)
top OTC meds?
- cough and cold ($8.2 billion)
- pain reliever ($4.1 billion)
- antacid (2.7 billion)
- toothpaste (1.5 billion)
- laxative (1.3 billion)
3 important considerations
safety, indication (what to use for and use), counter-indications
dose makes the ___ and ____?
drug and poison
what is most common OTC drug
pain killers ($4.1 billion)
what is salicylates
found in willow trees and Sumerians used for pain and inflammation
also in poplar, beech and wintergreen
what is doctrine of signatures?
association between disease and cure (ex ppl who lives near swamps get malaria and willows grow in swamps)
willow bark will cure ___ and what is active ingredient?
fever and salicin
when was salicylic acid was discovered in
1829
salicylic acid is ____ and where does it come from?
analgesic, antipyretic and antiflammatory and comes from coal tar
Felix Hoffman
took salicylic acid for pain and suffered from stomach problems
process of drug optimization is?
changed the chemical structure and taste less bitter with no stomach irritation (salicylic acid to acetasalicylic acid)
aspirin initially sold as ??
sold as a powder
what is ASA
acetassalicylic acid (same thing as aspirin)