mental health Flashcards

1
Q

what is the body

A

chemical based machine

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2
Q

what does mental illness have

A

genetic component

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3
Q

mental illness history?

A

thought tp be caused by demons = trepenation (treatment) and were often tortured with asylums and prisons

electrotherapy often used

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4
Q

when was psychotherapy made and by who

A

freud 1896

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5
Q

what was lobotomy 1940s

A

needle thru eye socket

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6
Q

when did lunatic asylums become mental hospitals

A

1950s

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7
Q

schizophrenia?

A

loss of contact and reality

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8
Q

Sid effects of schizoprenia

A

hallucinations and delusions of persecutions

auditory, confused thinking, magical thinking, false beliefs, anxiety and feelings of persecution and lack of emotion

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9
Q

what did they use to calm down patients with schizophrenia

A

antihistamines and thorazine

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10
Q

side effects of thorazine (dopamine antagonist)

A

similar to Parkinson’s disease, grimacing and dyskinesia and lip smacking

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11
Q

what is the theory of schizphrenia

A

high dopamine causes it

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12
Q

what raises dopamine amounts in brain

A

amphetamines

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13
Q

what are the 5 receptor types of dopamine antagonism

A

d1 - d5 (d2 most important)

allows dopamine use in diff parts of brain and creates diff pathways for dopamine to transfer info

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14
Q

how was subsequent drugs found?

A

in animal studies and found patterns of behaviour of drugs

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15
Q

what is chlozapine

A

weak d2 dopamine antagonist and strong serotonin agonist (less likely to cause motor control side effects)

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16
Q

what is depression

A

loneliness and sadness

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17
Q

what is anhedonia

A

inability to experience pleasure

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18
Q

what is tricyclic antidepressants

A

discovered in 1951 and not effective for shizophrenia

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19
Q

what sends nerve signals

A

physical transfer of neurotransmitters

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20
Q

what blocks serotonin reuptake

A

imipramine (side effect: designs new drugs effects to be more selective)

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21
Q

what is ipronazid

A

tuberculosis drug, antidepressant and has monoamine oxidase (MAO)

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22
Q

what is MAO

A

helps regulated neurotransmitter amounts, body controls amount of chemicals by constantly making and destroying them

MAO blocks the enzyme (increase amount of serotonin in brain and reduces serotonin destruction)

23
Q

what does depression rise from

A

arises from low serotonin amounts

24
Q

what is selective serotonin reuptake inhibitor (SSRI)

A

prozac was first and side effects: anxiety, sleep disturbances and sexual dysfunction and suicidal thoughts

25
Q

what is prozac

A

no difference between placebo and prozac

26
Q

OCD affects ??

A

2%

27
Q

what is OCD

A

obsessive thoughts and unrealistic

28
Q

compulsions performed to gain relief

A

rituals

29
Q

helpful drugs for OCD?

A

raising serotonin activity, prozac, MAO inhibitors

30
Q

theory of OCD

A

low serotonin function produces OCD

31
Q

bipolar disorder

A

alternate between high energy happy periods

32
Q

what calmed mani patients with manic depression

A

lithium calmed manic patients

33
Q

why is it hard to design new drugs

A

because of lithium structure

34
Q

difference between effective dose and dangerous dose is ???

A

very small

35
Q

why is lithium mechanism of action not known?

A

no known lithium receptor

36
Q

what is valproic acid

A

anticholinergic drug

37
Q

anxiety disorders

A

fear without reason

38
Q

what are barbituates

A

GABA agonists (reduce neural activity)

39
Q

what do benzodiazepines do?

A

amplify GABA and increase sensitivity of receptors

40
Q

GABA activates a special receptor called?

A

ion channel (Valve)

41
Q

what are psychiatric drugs side effects

A

headaches, nausea, anxiety, sexual dysfunction and depresson

42
Q

drugs in 2016 same effectiveness as drugs in 1950s?

A

true

43
Q

modern drugs show fewer witch side effects?

A

anxiety, sleep disturbances and dysfunction

44
Q

why are human experiments hard to do

A

can’t fully control what people do and difficult to measure brain activity

45
Q

what did drugs used to develop?

A

pattern of behaviour

46
Q

what is swim despair test?

A

swimming, struggling or floating

47
Q

hotplate pain test??

A

puts feet up

48
Q

how is animal models used

A

alters brain and uses drugs to induce change

49
Q

me-too drugs

A

kinda copies of existing products

50
Q

what are effects of me too drugs

A

produced in animal models and use old drugs as a starting point

51
Q

what does prozac produce

A

immediate effects in brain

52
Q

patient’s noncompliance with treatment?

A

20-80% non compliance, stops taking meds and takes them improperly

53
Q

why are patients noncooperative

A

takes them improperly, misunderstanding, side effects and resist treatment and false beliefs + financialdru

54
Q

drugs for mental health do work?

A

true