Paediatrics Flashcards

1
Q

Nocturnal Enuresis PE 0170
P enuresis
P enuresis with daytime symptomes
S enuresis (search cause) - Refer to Pediatrician

A

1) Primary enuresis = NIGHT bedwetting only! -
<5 years: reassure -
> 5 years and bedwetting less than twice/week= reassure

  • *NB if mother wants a short term ttt (child going to sleepover at his friend’s house for ex) = desmopressin
    • If long term ttt= Alarm then reward

1) Primary enuresis with daytime symptoms
a child thats bedwet at day time REGARDLESS of age
Referred to an ENURESIS clinic or SECONDARY care.

DAY TIME: 1. bladder retraining 2. oxybutynin 3. oral/SL desmopressin
NIGHT TIME: 1. enuresis alarm 2. reward system

2)Secondary Enuresis: - A child that has been dry for at least 6 months and now consistently bedwet at night -

1) EMOTIONAL UPSET ( child abuse)
2) 2ry to infection and diabetes.

**Urine/ Glucose test
Culture for infection —>
if -ve= refer to pediatrician!

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2
Q

Bronchiolitis or Pneumonia in UK 4 week old with bilateral basal crepitation and T 38.4 and Tachypnoea ?

A

T>39, FOCAL crackles- PNEUMONIA

otherwise the most common in this age group is BRONCHIOLITIS
babies and children under 2 years of age and
most commonly in the first year of life, peaking between 3 and 6 months.

  1. Bronchiolitis is more commonly seen in healthy children born at term whereas pneumonia is more common in children with some underlying disease, preterm birth or a history of preceding viral infection.
  2. Pneumonia will usually present with more than 39 while bronchiolitis has fever less than 39.
  3. Pneumonia commonly has focal findings on auscultation while bronchiolitis will have more widespread findings.
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3
Q

Diarrhoea Differentials

A

travel + wt loss(in chronic case)+ watery D. + long duration + abd distention = giardia travel
Tx - rehydration plus metronidazole

watery D. + short duration + abd. crump = E. coli

bloody diarrhea = campylobacter jujeni / Salmonella and Shigella

bloody diarrhea after long term Antibiotics = clostridium difficile ( pseudomembarenous colitis)

bloody diarrhea: Campylobacter Jejuni
Traveler’s Diarrhea: E.Coli

Diarrhea in paeds: Viral (Rota Virus)
Diarrhea(GIT Infection) + weakness+ Areflexia : Guillian-Barre Syndrom
Diarrhea followed by RUQ pain: Amoeba Watery
Diarrhea after camping or long travels in Europe: Giardia Diarrhea
D after long-term antibiotics: Clostridium Difficle
Diarrhea after eating raw eggs or chicken: Salmonella
Diarrhea just hour after a meal: Staph Toxin
Diarrhea in bed ridden pt (e.g handicapped) + stony hard stools : Fecal impaction

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4
Q

Cough ddx

A

Epiglotitis….
Stridor + drooling of saliva n fever … (thumb sign L.Xray)
CALL anasthetist / Intubation of ET tube and Antibiotics

Bronchiolitis…. (Most common in children UK >pneumonia )
Cough fever +sob+ expiratory wheeze + bilat basal crep
humidified oxygen

Croup…
Barking cough+stridor…. (steeple sign)
oral dexamethasone

Pertussis.
Episodic severe cough+ fever n cyanosis….
Clarithromycin or Azithromycin

Scarlet fever
Sore throat/cough,fever n RASH …
.Antibiotics

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5
Q

Child fall while playing / with Subconjunctival Hemorrhage / You are FY2 DR/ X ray head or CT

A

X ray for confirmation and CT for diagnosis (as you are FY2 dr you can request Xray)

subconjuntival hemorrhage is the bleeding within the eye,
whereas racoon eyes/panda eyes/ periorbital ecchymosis is the accumulation of blood (that seeps down from the skull fracture) within the periorbital soft tissue.

so CT needed in case of racoon eyes and not for subconjuntival hemorrhage.

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6
Q

Scarlett Fever (2-8 yr / Fever / rash / sore throat / )

A

Caused by ( GAStrep or Streptococcal Pyrogens ) not Stap.A

(S)carlet fever: 7S; - 
Streptococcus pyogen - 
Sore throat with pale exudate - 
Strawberry tongue - 
Sandpaper RASH on the (TRUNK) - 
Spare sole and palm rash - 
around Six yr age (2-8 yr) - 

Rx: Penici[S]lline V

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7
Q

Best consideration for Vesico-Ureteric reflux PE 4050

A

Ab Prophylaxis should be considered prior to Considering surgery (low reflux )

UV reflex does not cause renal scaring
UTI causes renal scarring and damages the most at early weeks of age

only surgical correction in two cases»»

1) breakthrough UTI infection despite prophylactic antibiotics
2) persistent high grade VUR (4 or 5 ) with renal scaring

Surgery correction is generally reserved for Hight grade reflux

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8
Q

Umbilical Granuloma

A

Umbilical granuloma -
a red bump on baby’s navel after the cord falls off & dried -
it’s usually harmless unless infected

1st line : Table Salt (Simple & effective)
salt draws water out of the wet granuloma resulting in necrosis and shrink

2nd Line : Silver Nitrate (no improvement with Na 1 wk )

If pus seen + fever etc - Apply Fusidic Acid

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9
Q

Lymphangioma (cystic hygroma) / Brachial cyst / Thyroglossal cyst

A
Lymphangioma : 
antero-Lateral to sternocleidomastoid muscle, 
Light translucence positive , 
Lymph present (soft and compressible), 
Age < 2 years(90%) Rule of L's. 
Branchial cyst: 
Antero-medial to sternocleidomastoid muscle, 
Hemorrhagic fluid present , 
Non-compressible, Non-translucent , 
Age=Early adulthood.
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10
Q

Non accidental injury Ddx

admit > analgesia > treat urgent medical condition > registered protection officer> social services

A
Non blenching Bursing Ddx 
HS purpura 
Haemophilia 
ITP 
Leukemia 

Fracture Ddx
Osteogenesis imperfecta - BLUE SCLERA , dental abn , brittle bones (Auto Dominant )

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11
Q

UTI in child Spiceman collection (clean catch / catheter / suprapubic aspiration)

A

1) Dip stick analysis of urine (+Nitrate and ±Leukocytes )
2) Urine Microscopy
3) Urine Culture

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12
Q
A

Malrotation and Volvulus- (neonate ) volve= rotate (twist in the intesting surrounding the mesentry )
(child - midgut / surgery need / adult - caecum and sigmoid / rerotate with colonoscope)
Sudden billious vomiting +
blood per rectum +
double bubble in X ray

Hirschsprung-----or congenital/toxic megacolon... (No peristalsis / nerve plexus or ganglion in colon (esp descending ) doesn't develop / resulting continuous contraction and  constipation )
may lead to sigmoid volvulus 
abdominal distension + 
failure to pass meconium + 
repeated vomiting 
Cystic Fibrosis-----
meconium ileus+  ( most children with thick meconium in ileus have cystic fibrosis)
failure to thrive +
Bilious vomiting 
Echogenic USG on perinatal USG 
Duodenal Atresia-
vomiting large amt bilious or non bilious, (right after birth / pass stool 2 times/ then no bowel movement ) 
abdominal distension , 
no passage stool, 
jaundice + double bubble sign 
Necrotising Enterocolitis--- (most common GI infection in premature babies)
premature or low weight bith+ 
bloody stools+ 
abdominal distension+
bilious vomiting.
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13
Q

Vitamin D take or not take

A

Babies having 500ml or > Formula Milk / DO NOT NEED VITAMIN D

All adults including babies need to take Vit D 400IU / 10mcg per day (also Caucasians )

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14
Q

Fever with Rash (Measles / Scarlet Fever / Rubella / Erythema Infectiosum) PE 0330

A

Measles(Rubeola) -
macules and patches / on face / neck and shoulders /
Koplik spots /
no cervical lymphadenopathy

Scarlet Fever -
sorethroat / strawberry tongue / sandpaper rash /
tender cervical lymphadenopathy

Rubella(German Measles) -
Pink macules and papules /
on forehead then to face/ trunk / extremities on 1st day/
Fades on face on first day and the rest of the body by third day
Cervical lymphadenopathy

Erythema infectiosum (Parvovirus B19)- 
Slapped Cheek appearence
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15
Q

Measles / Scarlet fever / Rubella

A

Measles - Koplic spots on Buccal mucosa / No cerval Lnodes
Rubella - Forshheimer spots on Soft palate / Cervial Lnodes
Scarlet fever - Sorethroat /

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16
Q

Neonatal Jaundice(24 hr or 2 to 14 days) / Prolong Jaundice (>14 days )

A

Pathological within the first 24 hours

Start form 2-14 common (40%) and PATHOLOGICAL
Seen in Breast Fed Babies

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17
Q

A child with 2cm lymph node and growing in size over 6 wk/ Immobile and non tender
No fever , wt loss , tiredness , signs of infection / Most app investigation

CP / USG / Infection screen

A

Full blood count and Blood Film for leukemia and lymphoma

Hodgkin lymphomas in 75 % of cases have no B symptoms (loss of wt, night sweat and fever)….they will present with enlarged cervical LN and be asymptomatic otherwise

ALL is the most common leukemia in peads.
AML is more of acute sympt. Like Gum bleeding.

  • If lymph nodes after infection (reactive lymphadenopathy) -> reassure
  • If >2cm or progressively enlarging Firm/ nontender/ hard

With fever/ weight loss/ night sweats Refer urgently.
1st test is FBC: if normal then ALL unlikely,
perform Excision biopsy to rule out lymphoma If FBC abnormal then do peripheral smear to look for blast cells.

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18
Q

Woff- Parkinson-White Syndrome

Wolf = DOg delta waves

A

breathless and palpitation following exercise followed by rapid recovery
inv - ecg,24 hours ecg holter
ecg- delta P wave, Pre-exitation pattern,
short PR, prolong QRS
rx- catheter ablation medication- flecainide, propafenon

AV-node pathway blockers:–
1) b-blockers, 2)ca-blockers(verapamil,diltiazem), 3)adenosine.

Accessory pathway(AP) (Kenth pathway in WPW$) blockers:-

1) Procainamide, propafenone,flecainide
2) amiodarone &sotalol

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19
Q

Respiratory Distress Syndrome in Infants
More common in < 32 weeks gestation
CXR - Ground Glass appearance

A

Premature infants / CS deli / Maternal DM / MAS

Tx - Endotracheal Surfactant Replacement
Intermittent PPventilation

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20
Q

MAS (Meconium Aspiration Syndrome )

More common in Gestation > 42 weeks / Maternal HT / Oligohydramnios

A

Meconium - stained Amniotic Fluid
Cxr - aspiration pneumonitis

Tx - Airway SUCTION
O2 / Fluid and electrolyte Balance

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21
Q

UTI not responding to antibiotics after C and sensitivity
DMSA (done only in small babies and 4-6 weeks after UTI resolve and clear)
MCUG(can be done during UTI for recurrent and atypical UTI)

A

If child responds to treatment to UTI within 48 hours,
Ultrasound is arranged in 6 weeks .

If child doesn’t respond well within 48h,
then MCUG to detect VUR.

IF VUR presents then DMSA in 4-6 months to assess renal scarring.

6-month baby DMSA to search for renal scarring
6-3 years consider DMSA in atypical and recurrent UTI
>3 year not DMSA

Mituration Cystourethrogram - 6-3yr old child UTI no improvement 48 hr after Antibiotics
in atypical and recurrent UTI

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22
Q

Neonatal Jaundice ddx

A

Prolonge jaundice: >14 days Unconjugated>Child is well> Breast Milk Jaundice

Unconjugated>started at day 1> child well> Gilbert

> failure to thrive>HepatoSpleenoMegaly > Galactosemia

Conjugated>No fever>Biliary atresia/Torch

Conjuagated> protruded tongue> Hypothyroidism

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23
Q

Pyloric Stenosis Vs GERD

A

PS- non bilious vomiting AFTER BIRTH
Constant Hunger and Weight LOSS

GERD - recurrent vomiting and cries shortly after FEEDS
REFUSAL of feed / growing well and normal weight
- Rx Gaviscon (antacid with coating and last 24hr)

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24
Q
Necrotizing Enterocolitis (CL0080)  (Intestinal Barrier Dysfunction ↓ IgA)
Premature Birth(weak Blood supply) and Formula Feeding(weak immunity)
A

The smaller and earlier the baby, the higher the risk for NEC.
not enough blood and oxygen reach your baby’s immature intestinal tissues

Dx
Bell staging (Radiological Signs )
Stage 1 - ileus / dilatation
Stage 2 - pneumatosis intestinalis (air in intestine) / Portal Venous Gas (Met Acidosis)
Stage 3 - pneumoperitoneum (Met Acidosis )

Tx
Stopping enteral feedings,
performing nasogastric decompression, and
broad-spectrum antibiotics - Pen /. Genta / Metro
Pneumoperitoneum - Surgery

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25
Q
A

painless rectal bleed in Meckel’s Divertaculum

painful bleed in Intussusception and Volvulus

intramural air in Necrotizing enterocolitis

non bilious projectile vomiting in Pyloric stenosis

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26
Q

Galactosaemia

A

Galactosaemia
term infant gets an E. coli sepsis and when a neonate develops cataracts. It should also be considered with neonatal jaundice and haemorrhage.

Inability to metabolize galactose( a sugar in milk)
Accumulation In brain
Eye –Cataract
Kidney —Kidney damage
Liver… Liver damage..
No conjugation.. Unconjugated bilirubinememia..
Stool yellow and no change in urine

Hypothyroidism
impairs bilirubin conjugation, slows gut motility and impairs feeding leading to hyperbilirubinemia.

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27
Q
Dehydration 
Mild   -decrease urine output 
5%     -plus dry mucus membrane 
10%    -plus sunken fontanelle 
>10%  -plus shock (CRT>3sec, rapid thready pulse, ↓ Skin turgor, tachycardia & tachypnea (60,50,40rule), cold peripheries )
A

Rx -
if only just dehydrated & can tolerate oral feeds > ORS

if in shock -> Give IV bolus dose of 0.9% NS @ rate of
100ml/kg for first 10kg
50ml/kg for next 10kg
20ml/kg for anything after 20kg total

For maintenance –> 0.9%NS + 5% Dextrose

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28
Q

PM 5000 7 day baby initial birth weight 3.5kg now 3.3kg / What to do next

A

Reassure / Continue Child Care

5-10% wieght loss in first days after delivery… Is normal

14 days to gain weight more than birth weight.

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29
Q

Rash in Children and When to return to School PE 0230

A

Cannot Return to School (S.I.C.K Miss Ruby )

Scarlet Fever
away form school until 24 hr after staring Abiotics

Impetigo
away form school until 48 hr after starting Ab or Lesions are Crusted or Healed

Chicken pox
Until VESICLES have Crusted or Healed
5 days after onset of rash
keep away form pregnant women also

Measles / Rubella
4 days after onset of rash

Can return to School (Her simple Molly Rosey is Partying )
Rosella
Parvo virus B19 or Slapped Cheek or the fifth disease or Erythema infentiosum (once rash has developed / self limiting / symptomatic tx)
Molluscum contagiosum
Herpes Simplex (cold sores )

Chicken pox–fluid filled blisters (centripetal distribution)
Rubella :white spots on soft palate plus Swollen lymph nodes
Measles: koblic spots on buccal mucosa
Roseola: sudden onset fever plus chest rash
Parvo: slap shaped distribution sparing nasolabial folds

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30
Q

Nephrotic Syndrome

7 year old kid with 2 day leg odema / no other problems

A

2-3 months of Corticosteroids reduced Sodium intake and
if SEVERE - – Fluid restriction and use of Furosemide.
Steroid dependent Nephrotic – IV Cyclophosphamide

PROteinuria >3g per 24 hr , HYPOalbuminemia < 30g per liter: NephROtic syndrome
proteinuria <3 , hematuria : NephRItic syndrome

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31
Q

Cow Milk Allergy
If CMA is suspected and reaction is Acute - IgE mediated
If CMA is suspected and reaction is Delayed - (Reflux , Loose Stool , Growth ↓) - Non IgE mediated

A

IgE Mediated cow’s milk protein allergy–
Acute —–skin prick/blood test [for acute, condition —
INVASIVE INVESTIGATION is ACCEPTED

NON IgE Mediated —
Not acute presentation —–so stopping cow’s milk and
substituting with hypoallergenic
{HYDROLYSED FORMULA } FOR 2 WEEKS CAN BE TRIED ,
IF NO IMPROVEMENT—-Amino acid formuls can be tried

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32
Q

Signs of SHOCK and Severe Reflag Dehydration in P
Normal Capillary Refill time < 2 sec
2 yr old child can have HR within 80-120 / RR 20-30
Weigh loss no rule in Dehydration

A

Signs of clinical shock in pediatrics: -
**Decreased level of consciousness. -
Pale or mottled skin. -
Cold extremities. -
Tachycardia. - Tachypnea. -
Hypotension. -
Delayed capillary refill. (4 sec)-
*******Weak peripheral pulse.

Signs of reflag severe dehydration in Pediatrics
↓Urine output
Sunken eyes
Dry mucus membrane (except for mouth breather)
Tachy / Tachypnea
Reduced Skin Turgor

33
Q

PE 5011 2yr old Child with night stridor / temperature 38 / RR 31 / PR 140 / O2 99% but no chest wall recession / percussion resonance
for 3 nights what will happen if left untreated / most likely complication

A

STRIDOR (upper air way obstruction )- Coup
WHEEZING (lower air way obstruction )- Bronchiolitis <2 year with fever 38
Most children Complete recovery (with or without tx ) oral dexa
ARDS will not happen
Its a case of UNCOMPLICATED Coup (laryngotracheobronchitis )
with peak incident 6mth - 3 years

34
Q

Coagulation Pathway (2 pathway which Activates COMMON PATHWAY)

A

Damaged Vessel have
TISSUE EXPOSURE and PLATLET DEPOSITION

Extrinsic pathway start with TISSUE FACTOR / 7a

Intrinsic pathway start with PLATLET / 12a / 11a / 9a

Extrinsic (7a + Tissue factor )
or
Intrinsic (9a + 8a )
(In HAEMPHILIA factor 8 defiency in type A and factor 9 defiency in B)
CAN ACTIVATES Common Pathway 10a /5a / 2a(Thrombin ) / 1a(Fibrin) and 13a

1a + 13a CREATES MESHES AROUND THE PLATLET to make them FIRM and HARD

35
Q

Hemophilia A and B
Platelet is normal
Pro time is normal
Partial Pro time is prolong (Factor 8 or 9 defiency )

A
Prothrombin time 
test Extrinsic (Factor 7)
 Common Pathway (Factor 10 5 2 1 13)
Partial Prothrombin time 
test Intrinsic  (Factor 12 11 9 8 )
Common Pathway(10 5 2 1 13)
36
Q

2 year old child Lost in Shopping Centre / Become Upset / Fall down / unconcious

A

Breath Holding Spells

Reassure

37
Q

Kawasaki Disease

A

Strawberry tongue

38
Q

Cystic Fibosis

A
Sweat test (>98% Sensitive Chloride >60)
Genetic test (Carrier test for partents )
39
Q

NICE Red Traffic Features

A

Red Traffic (High Risk) features: -
Pale/Mottled/Ashen/ Blue skin. -
NO Response to Social Cues. (No Response At All!). -
Appears ‘‘ill’’ to a healthcare professional. -
Does not wake, Or,
if Awaken (Roused) Does not stay awake. -
The cry is either weak Or high pitched Or continuous. -
Grunting (Not Flaring, Flaring is Yellow Traffic-Intermediate- Risk). - Respiratory Rate > 60 -
Moderate or Severe Chest Indrawing. -
Reduced Skin Turgor. - (Mild dehydration sunken eye also)
Age < 3 months with Fever=> 38. -
Non-Blancing Rash. - (Bact meningitis )(other Ddx HUS/ HSP / ALL / ITP )
Bulging Fontanelle. -
Neck Stiffness. -
Status Epilepticus. -
Focal Seizure. -
Focal Neurological Signs.

40
Q

Malrotation and Volvulus or Intussusception CL 0061

A

1) bilious vomit rules out pyloric stenosis
2)duodenal/jejunal atresia are ruled out since he is passing blood with stool which is not seen in them.
Usual picture is obstruction (no stool) and abdominal distention with bilious vomit
3)appendicitis vastly different clinical picture

4)confusion is bw intusussception and volvolus while bloody stools and bilious vomit is common in both but —-

***intussusception will say things like 
'"currant jelly red stools"' and 
'"raising legs while crying"' and 
''donut/target sign'" and 
"sausage mass"" and 
"claw sign" 

**while malposition and
double bubble point towards volvolus
**
lastly Volvolus mostly occurs in First month of life and

intusussception occurs mostly after 6 months kindly correct if anything wrong

41
Q

ITP (isolated thrombocytopenia)< 20000

CL007

A

Sudden onset of Petechiae and Bruising on the arms and legs
25% Nosebleeds
commonly after Viral infection of URTI or Vaccination

Primary ITP
immunoglobin against platelet which carries the platlet to the spleen to destroy

Mgx

Low risk tx (petechial / large bruises without active bleeding )
Conservative

Moderate risk tx (Epistasis for > 5 minutes ) (<20 X 109 without life threatening symp)
Admitted to Hospital and
Oral Prednisolone (1st line )
If fail to increase platelet after a few days IVIG(2nd line )
IVIG also before surgery to increase platelet

High risk tx (Internal haemorrhage ICH / Muscles and Joints )
Admission and Prednisolone + IVIG
other Tranexamid acid

42
Q

Roseola Infantiosum / Child fever 39-40 rash / but eat and sleep normally
VR1001

A

Roseola infantum, also known as sixth disease, is caused by infection with
human herpes viruses 6 and 7 (HHV6 and 7).
severe pyrexia 39-40 for 3-5 days alongside rhinorrhoea and fatigue,
then on cessation of the fever an exanthem will appear on the face and body. It most commonly affects children between 6 months and 3 years of age

Herpes 1/2 - oral / genital ulcers = herpes simplex virus
Herpes virus 3 - varicella zoster = chicken pox
Herpes 4 - epstein barr = mononucleosis
Herpes 5 - Cytomegalovirus
Herpes 6 - Roseola
Herpes 8 - kaposi s sarcoma

43
Q

indications for immediate IV access in pediatric and neonatal cases

A

cardiopulmonary arrest,

major burns

prolonged status epilepticus

hypovolemic shock septic shock if IV line attempt unsuccessful within 60-90seconds,

attempt Intraosseous line.

44
Q

Infantile Spasms VS Breath Holding Spells

A

Infantile Spasm/ West Syndrome/Saalam attacks

baby doing apparently well suddenly has jerky movements :

SYMMETRICAL FLEXION of NECK & EXTENSION OF ARMS + maybe associated with Down’s syndrome (more prevalent) + No fever + Learning problems/Developmental delay

Cause - due to brain injury- idiopathic/acquired (down’s)

Ix - EEG (shows hyper arrhythmia)
Rx- ACTH dept / Prednisolone/ Vigabatrin

Breath Holding Spells
child lost with parent / or fells down while playing tricycle / stairs
hold breath

45
Q
  1. Cystic fibrosis increased viscosity of mucus dt Cl channels
  2. Kartanagers syndrome ciliary dysfunction
A

Kartagener’s Syndrome autosomal recessive defects ciliary function. common association with Dextrocardia. present with recurrent pneumonia, chronic rhinitis and otitis media and later bronchiectasis and infertility. airway biopsy for microscopic examination of the cilia is diagnostic. long term prophylactic antibiotic with chest physiotherapy carries good prognosis

46
Q

6 month old boy / persistent irritability and lethargy

A

1) LESS than 3 months- do microscopy and culture and refer / NO DIP STICK

2) 3moths to 3yrs- both or either Nitrites and Leukocyte esterase
positive-
start antibiotics and send for culture.

both negative- nothing

3) 3yrs and older-
both positive- treat it/

both negative- do nothing/ nitrites positive- treat and sent culture/ leukocyte positive- send culture and WAIT.

47
Q

Osteogenesis Imperfecta:

A
  • Brittle bones
  • Blue sclera
  • Hearing loss
Tx: 
IV Bisphosphonates (PAMIDRONATE)
48
Q

Overactive Bladder Syndrome (Only day time symptoms )

P bedwetting syndrome (always Night symptoms ± day symptoms)

A

OABS :

1st line - Bladder Training for 6wks ( Stepwise Scheduled Toileting+ Behavioral Therapy)

2nd line - Oral Oxybutynin (anti-cholinergic)
Oral or Sublingual Desmoplasin

49
Q

Systolic Murmur in Down Syndrome / Possible causes ?

A

The top 3 common cardiac defects in down syndrome are:
1. Endocardial cushion defect lead to AVSD ( the most common ).

  1. VSD ( the 2nd common)
  2. ASD ( the 3rd common)
50
Q

Non accidental INJURY in children

Spiral Fracture of the HUMERUS

A

Due to twisting and sudden pull with force by an adult

51
Q

PE 0571
4 yr old VESICLES on the Parm and sole / Ulcer on the mouth
T 38

A

Hand foot and mouth disease
Coxsackievirus
IF THE CHILD FEEL WELL ENOUGH TO GO TO SCHOOL / NO NEED TO ISOLATE
Ibuprofen used for sympetatic relief

If you see Palms and soles(which are hard to have vesicles by other infections) always think of Hand Foot and Mouth(HFMD) disease; Caused by CoxSackie virus

Leisons of measles are MACULOPAPULAR not vesicular. Koplik spots are whitish leisons in buccal mucosa with pale centres

palm and sole RASH: Kawasaki disease hand foot mouth disease secondary syphilis

52
Q

Chest Cough + Jaundice ? PE 1799

A

Chest + liver= alpha 1 antitrypsin defiency (inhibit elastase) (Elastase digest elastin in alveoli = Emphysema / Copd )

Chest +brain =Wilson

Chest + GIT = Cystic Fibrosis

Chest + kidney = Goodpasture syndrome.

53
Q

Non Blotchy Purpura (do not turn white when pressed)

H.IT / Me / ALways

A

** Bact Meningitis ** - Neck stiffness / Photophobia / altered mental state
ITP - Burses after a fever / isolated thrombocytopenia
HSP (small vs vasculitis)- Asso with abd pain / rush on buttock and extensor of hand /IgA↑
HUS - (Anuria / Oliguria ). (E.coli / Diarrhoea illness ) (Anemia / Low platlet)
Acute Leukaemia - Lymphadenopathy / Slow onset / Anaemia

54
Q

PE 2505
<2year old child with Fever 38 and substernal resection and Wheeze
Wheeze = lower RT obstruction
Coup = upper RT obstruction

A

2-6 month Wheeze and fever = Bronchiolitis / 2-6month
Tx - Supportive care with Nebulized Oxygen
NICE RECOMMENDATION - LARGELY SUPPORTIVE
Antibiotics
Hypertonic saline

other Ddx
>39 Pneumonia focal crep
No wheeze / Barking Cough - Coup

55
Q

Congenital Hypothyroid

A
56
Q

Weight Calculation in Babies for NON ACCIDENTAL INJURIES

4 month old = 6.8kg / not 4.2kg

A

weight of
infants 3-12 months age = age in months + 9 divided by 2

for children 1-6 years)= age x 2 + 8
>8 years) = age x 3

57
Q

CS 3330

Asthma distractor

A

Anaphylaxis

58
Q

Mother 8days after giving birth positive Varicella Zoster (7 days before or after giving birth)
Infant is well / what to do next

A

Mother need 7 days to develop IgG antibodies and give it to infant via Placenta or newborn via Breast Milk

Need VZIG immunoglobin within this time frame
-7__________________birth_________________+7

if a mother develops pox
more than 7 days before or 7 days after birth no need for VZIG
within 7 before birth or 7 days after birth isolate and give IG

if the neonate develops pox
give acyclovir with 24h

if preg with no previous exposure contact with pox person
give IG within 10 days

if preg and develops pox
give acyclovir within 24h

complication of pox
congenital varecela when preg
pneumonia and hepatitis when delivered

59
Q

Difficulty learning and writing at 7 years of age Which Social Service to Refer

PE 1570

A

Educational psychologists - for children with learning difficulty to achieve their full potential

NOT speech and language therapist (SALT) - for Post Stroke patient
for swallowing and speaking

60
Q

Pertussis Whooping Cough / Bordetella Pertussis

Notifiable disease

A

Blouts of Cough / Cough Vomiting / Asphyxia and Cyanosis after cough in infants

Paranasal Swab test and Nasopharyngeal aspiration (Difficult in child) test
within 2 weeks of cough
Culture (Gold standard)and PCR (done together with culture)

Tx: Antibiotics Macrolides- Azithromycin or Clarithromycin

61
Q

PE 3901
5week old Sticky LEFT eyes without red eyes / no lid swelling

What to do next /

A

Blocked nasolacrimal duct (most common cause of eye discharge < 12 months )
Sticky eye without purulent = Blocked Nasolacrimal Duct
Reassurance / Simple Massaging of the ducts

Red eye + Sticky discharge = Secondary Care
Purulent discharge after birth = Primary care will have already taken for Chlamydial

62
Q

16 yr old child with DM , goes hiking , penetrating wound to his left foot
dev ulcer / REFUSE TO BEAR WEIGHT / fever / Causal organism

A

Osteomyelitis(Streptococcal Aureus) including MRSA

In Children Long bones are most commonly affected
Tibia / Fibula / Humerus
Streptococcal Aureus

63
Q

Child Cystic Fibrosis(Auto Recessive ) with chronic cough for 2 year
on Antibiotics
****CHEST Physiotherapy****** comes first

PM 1117
PM 1116

A

CF in children
Staph aureus then H influenzas.

CF in teenage and adults
Pseudomonas.

Repeated chest infection.. Bronchiectasis… Ttt physiotherapy # antibiotics…
Exacerbation and prophylaxis till 3_6 years

SWEAT CHLORIDE test / DNA / Nasal Potential Difference
P New Born Test Guthrie test

Complication (all are obstruction with Thick mucus / )
Failure to thrive dt mal absorption
Lungs - Bronchiectasis
Bowel - Meconium ileus (X ray / bilus vomiting)
Liver - Steatorrhea / Toxin cannot secret (Cirrhosis )
Pancreas- DM / Digestive enzymes self digest (Pancreatitis)
Reproduction - Both Fertile but blocked Tubes ↓fertility

TX
**CHEST Physiotherapy******
Bronchodilator
Azithromycin /Flucloxacillin is the antibiotic of choice. 3-6 years of age. for recurrent
Mucolytic
CFTR modulators (CL channels to work again )

64
Q

Congenital Pyloric Stenosis -

A
Male infant (9x more common in males) + 
projectile vomiting after each feed + 
Child always hungry+ 
>6wks baby*+ 
Faltering growth+ 
Visible peristalsis+ 
Olive sized palpable mass 

Ix- ABDOMINAL USG (1st line) - increased thickness of pylorus
Rx - Ramsted’s pyloromyotomy

GERD - crying after each feed / vomiting / no abd mass / Normal Growth

65
Q

Child with regurgdation

A

child with regurgitation
treat as GORD first
unless- 1. perianal redness 2. loose stools 3. erythema or atopic eczema

Treatment of GORD

  1. increase frequency , reduce amount per feed
  2. trial of thickeners
  3. gaviscon ( alginates)
  4. ppi for 4 weeks 2 is tried first followed by 3 and then 4

Treatment of non IgE cow milk protein allergy
first replace with Hypoallergenic formula
if does not help switch to Amino acid formula

66
Q

DDx of Non tender Cervical Lymph node in child over few MONTHS

A

Take Excisional Biopsy USS guided (Needle Biopsy will disrupt the architecture of the Lnode)
ALL - FBC - low RBC PT and high lymphocytes / lymphoblast
Hodgkin Lymphoma - Reed Stenberg Giant Cells
TB - constitutional symptoms

67
Q

HUS(Hemolytic Urinemic Syndrome ) or SHIGA TOXIN
DONT NOT GIVE Antibiotics and Antispasmodic(Loperamide)
Release More toxin when die
Supportive Only (80% good prognosis )
Child go to visit farm and come back with BLOODY diarrhoea/ blood in urine /

A

Causal Organism/ E coli and Shigella

Classical TRIAD
ANAEMIA / THROMBOCYTOPENIA / ARF + (BLOODY DIARRHOEA )

First Abdominal pain and BLOODY diarrhoea for 5 days and
they produce SHIGA TOXIN
cause blood clots to form ( use up RBC and PT / Deposit in Kidney / hypertension )
Anaemia / Haematuria / AKI / THROMBOCYTOPENIA brusing

68
Q

HSP (CHLD RHEUMATOLOGY) < 10 year age with purpura and join pain
IgA Deposition in Vessels after Upper RT infection and GE

A

CLASSICAL 4 symptoms

Palpable Purpura 100% (Must Have ) with one of these
Joint Pain 75% (Knee and Ankles )
Abd Pain 50%
Kidney Impairment 50% (Micro or Macro Haemat / Proteinuria )

69
Q

At HOME CHILD Jaundice within 24 hours SHOULD ring EMERGENCY AMBULANCE to Hospital within 2 hours

A
Transcutaneous Bilirubin Measurement
Liver Function Test
Direct Coomb's test
G6PD test 
Full blood count 
Blood film 
Blood group

to be seen within 6 hours (using clinical judgement regarding more urgent referral or admission)

if: - Jaundice first appears at more than 7 days of age. -
The neonate is unwell (for example, lethargy, fever, vomiting, irritability).
- Gestational age of less than 35 weeks. - Prolonged jaundice is suspected — that is a gestational age of less than 37 weeks with more than 21 days of jaundice; or a gestational age of 37 weeks or more with more than 14 days of jaundice.
- Poor feeding and/or concerns about weight, particularly in breastfed infants.
- Pale stools and dark urine.

70
Q

Prader Willi Syndrome

Chromosomal Not expressing at certain part due to Blocker

A

Infant - failure to thrive

Child hood - Over eating / Obesity / Delay mental development

71
Q

Coeliac disease vs Cystic Fibrosis (with cough )

Coeliac disease = Gluten allergy (autoimmune to protein Gluten) (no respiratory symptoms)
Inv - IgA transglutaminase Antibody or IgA endomysia antibody
INV -Alpha Gliadin antibodies positive
If TTG IgA / EMA is negative +IgA deficiency—–> perform IgG.*****
And if TTG is positive——-> perform EMA (IgA endomysial antibody).

A

Coeliac disease
All GI symptoms and Mal absorption

Chronic or intermittent Diarrhoea
Steatorrhea (stinking stools)
Persistent Bloating and N and Vomiting
iron B12 folate deficiency

72
Q

PE 0060
Streptococcus agalactiae ( a - decrease production of Galactic - MIlk in cows )
Preg women go S .agalactiae screen test

A

Streptococcus agalactiae,
group B streptococcus, is a gram-positive

It tends to cause invasive disease in high-risk populations including pregnant women, neonates and the elderly. Invasive group B streptococcus infections in adults tend to present as bacteraemia without an obvious focus.

73
Q

Streptococcus = Gram+ Chain cocci
Three big groups
1. Alpha Hemolytic (haemolysis blood only 50%)
2.Beta Hemolytic (haemolysis blood 100%)
3.Gama Hemolytic (no haemolysis of blood) … Streptococcus Faecalis and faecium (normal flora of gut)

A
Alpha Hemolytic contiains two types 
Strep pneumoniae (Macrolide sensitive)
Strep Viridians (Macrolide nonsensitive)

Beta Haemolytic Two subtypes
Group A streptococcus - Streptococcus Pyrogens
Group B streptococcus - Streptococcus Agalactia (Pregnant mom and neonate infection)

74
Q

CPR in children

A

INFANT = seal Mouth + Nose with mouth
Blow steadily over 1 second for 5 times
then 100-120 per minute rate compression
with two finger over the lower sternum (two finger method)
Or two thumbs over the chest (Encircling method)
30:2

LARGE INFANT = Seal one and try one with mouth
> 1 year old can use heel of hand over the lower half of the sternum to compress the chest
older children like adult cpr

75
Q

TCA overdose in Children

A

TCA in addition to Setrionin reuptake blockage

Blockes other 7 also
H Respiratory and Metabolic acidosis
Ach Dry mouth Dilated pupil Dry Mouth Dry skin Dry urine (urinary retention) Drowsiness and altered mental status
5HT
GABA
Alpha receptors Hypotension / Tachycardia
Na+ Prolong QRS complex
K + Hyperkalaemia / Tall T waves

Ds Investigations.. ECG, ABC, electrolyte panek

ECG… Wide QRS and hyperacute T
ABG.. Metabolic acidosis Electrolyte..
Hyperkalemia

Ttt..
Within one hour_____ Activated charcoal
Hyperkalemia and metabolic acidosis… NaHco3

76
Q

Constitutional delay in growth and puberty VS Hypogonadotropic hypogonadism
CDGP is diagnosis of Exclusion PE0021

A

Constitutional delay in growth and puberty
—– Short stature /No testicular development until 14 years or above hence no pubic hair.

hypogonadotropc hypogonadism ,they will provide us with some hormonal values some pituitary gland abnormalities… Without any such detail lab values or info It cannot b declared as hypogonadotrophic hypoggonadism

77
Q

CATCH 22
DIGEORGE SYNDROME
Chromosome 22 problem and ABSENT OF THYMUS

A
CATCH 22 ---------------------------- 
Cardiac abnormality 
Abnormal facies 
Thymic absence, 
T cell abnormality 
Cleft palate 
Hypocalcemia 

Chromosome 22

Failure to develop the 3rd and 4th pharyngeal pouches. Therefore failure to develop the thyroid and parathyroid which are derived from the 3rd and 4th pharyngeal pouches. Absent thymic shadow on X-Ray.

Thymic defect ¬» reduce T-cell immunity

Thyroid defect¬»hypothyrodism hypocalcemia fits
Truncus arteiosus & teratology of fallots
Tubular nose & cleft palate
Tolerism & hooded eyelid

78
Q

CZ 3540 Sudden Infant Death Syndrome

A