O and G Flashcards

1
Q

Post Pill Amenorrhoea

A

Normal : Amenorrhea up to 6 months / Wait for a spontaneous remission

If the patient is Anxious after 3 months : Give Clomiphene

After 6 months check USG for ovary for ovulation
Blood test for FSH LH and Oestrogen

Normal Levels :

  • FSH 5-20 IU/L.
  • LH 1.5-15 IU/L. ( Follicular Phase ) Up to 75 ( Peak of Cycle )
  • Estrogen < 10 pg/mL.
  • Prolactin :
    Non-pregnant 2-30 ng/mL
    Pregnant 10-210 ng/mL

Prolactinoma it’s supposed to be over 400 and
macroadenoma it is over 4000

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2
Q

Menopause and associated symptoms

menopausal woman with bleeding is always a sign of cancer - endometrial until proven otherwise.

A

Menopause + brown discharge—> endometrial cancer
Menopause + grey yellow purulent discharge —> infection

Menopause + painless bleeding after intercourse —> endometrial cancer Menopause + green discharge —> chalamydia

Bleeding within 1st yr of menopause —> follicular reactivation

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3
Q

sexually active / Menorrhagia / Dysmenorrhoegia or Fibroids not distroting the uterine cavity

A

Mirena IUS

If Mirena contraindicated

Assess for risk factors for OCP pills then give

If she has sickle cell anemia Then Depo will the first choice

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4
Q

Emergency Contraceptive Pills

A

Levo nelle pill 72 hr

IUD copper or ELLA ONE pill if 120hrs

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5
Q

Lower abdominal pain / Recent Amenorrhea / ± vaginal spotting

A
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6
Q

Antihypertensive in Pregnancy

A

Labetalol
If asthmatic - Nifedipine (also in post partum asthmatic )
If not suitable - Methyl dopa

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7
Q

Post menopausal bleeding is Cancer
especially endometrial cancer Until PROVEN otherwise

Transvaginal USG is the first line for endometrial thickness

A
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8
Q

Post menopausal bleeding is Cancer
especially endometrial cancer Until PROVEN otherwise

Transvaginal USG is the first line for endometrial thickness

A
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9
Q

Genital Herpes during Pregnancy Main rx- OB 4360

A

Women who are in the third trimester and develops first time genital herpes
Advised to Have oral Acyclovir until delivery and CS delivery

ORAL Acyclovir
 First exposure-
o 1st and 2nd trimester: • Acyclovir for 5 day
• Acyclovir from 36 week to delivery NVD
o 3rd trimester • Acyclovir upto delivery C/S

 Subsequent or recurrent
• Acyclovir from 36 week to delivery NVD

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10
Q

What Types of Miscarrages Via the USG ?

A

Complete: No fetus seen on US

Incomplete: Part of fetus seen on US

Missed: Dead fetus+Closed cervical os

Threatened: Alive fetus+Closed cervical os

Inevitable: Alive fetus+Opened cervical os

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11
Q

Failure rates of different Contraceptive methods

A

Failure rates of different contraceptive methods:

A. Permanent methods: -
Vasectomy= 0.1% or 1:1000 -
Tubal ligation= 0.5% or 1:200

B. Temporary methods: -
Condom (male)= 95% effective and 5% chance of failure rate -
Condom (female)= 5% failure rate -
IUCD= 0.6% - IUS (Mirena contains levonorgestrel)= 0.1% -
POP (progesterone only pill)= 0.3%

Contraception failure rates & duration of use:

  1. IUS 0.1% to 0.4% (3-6 years)
  2. IUD 0.8% (10 years)
  3. Implant 0.1% (3 years)
  4. Injection 4% (3 months)
  5. COCP 7%
  6. POP 7%
  7. Patch 7% (once per week then 4th week stop for menses)
  8. Male condom 13%
  9. Female diaphragm 17-27 %
  10. Tubal ligation 0.5%
  11. Vasectomy 0.15%
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12
Q

Peri menopausal symptoms
With hypertension and controlled with ACEi or SMOKER = Can give HRT patch (Oestrogen transdermal no effect on thromboembolism )

But in OC pills (Oestrogen not given to Controlled hypertension )

However Patch = much less Thrombo embolism Than ORAL OESTROGEN

A

Treatment of Post-menopausal symptoms:

  1. Life-style modification.
  2. If there is a uterus: - Combined hormone replacement therapy (HRT). -
    Another possible answer= transdermal estradiol and progesterone patches.
  3. If no uterus (H/O hysterectomy) or if there is IUS in place: - Oestrogen only HRT. - This is because progesterone is given with oestrogen to protect the uterus against endometrial carcinoma.
  4. If post-menopausal woman is a smoker: - HRT is given as transdermal patch, as oral route has higher risk for venous thromboembolism.

Types of combined HRT:

A. Sequential “cyclical” combined HRT: -
Used in the first 12 months of menopause or in perimenopause “still menstruating”.
Oestrogen is taken daily while progesterone is taken cyclically for the last 14 days of a menstrual cycle.

B. Continuous combined HRT: -
Used in menopausal women who have had their last menstrual cycle 12 months ago.
Both oestrogen and progesterone are taken daily.

***Perimenopause= still menstruating but may be irregularly or heavily near the age of 50 +/- other vasomotor symptoms.

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13
Q

Myoma treatment
If doent want child then symptomatic
If want child and intra mural - Myomectomy (GNRH given to reduce size before operation but it inhibits ovulation )

A

asymptomatic … follow up

menorhagia … IUS ( if not distortion ) , NSAID ,, COCS

severe menorhagia .. ellanova surgery …

need child … myomectomy surgery ….

doesnt need child ,,, hysterectomy or endometrial ablation ( if small less 3 cm ) ##

GNRH agonist beforee surgery is indicated

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14
Q

Anti HTN in pregnancy: LMN –Labetalol –Methyldopa –Nifedipine

A
In severe preeclampsia 
1- AntiHTN medication 
2- Mgso4 to prevent eclampsia 
3- CTG and USG to monitor the baby 
4- If>34 weeks give steroids to stimulate surfactant production 

deal with the cause (HTN!) before trying to prevent complications.

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14
Q

Anti HTN in pregnancy: LMN –Labetalol –Methyldopa –Nifedipine

A
In severe preeclampsia 
1- AntiHTN medication 
2- Mgso4 to prevent eclampsia 
3- CTG and USG to monitor the baby 
4- If>34 weeks give steroids to stimulate surfactant production 

deal with the cause (HTN!) before trying to prevent complications.

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15
Q

Lichen Planus Vs Vaginal Thrush

A

vaginal thrush(candidiasis):
white cheesy vaginal discharge +itching lichen sclerosis:
white plaques on anogenital skin+ itching at night
(tx:topical steroids,follow up 3 and 6 months because risk of scc of vulva)

lichen planus: white lacy pattern on oral mucosa

16
Q

Ectopic Pregnancy management OB 1257

A

asymptomatic (with visible heart rate ) —>methotexae

stable symptomatic or/and visible heart rate —> laparascopy

unstable —->laparatomy

17
Q

Anemia in pregnancy

If 33 weeks (U have enought 3 weeks time to correct anaemia with iron supplement)
but after 36 weeks Blood transfusion for quick refill (as there will also be blood lost during delivery )

A

1st trimester 1wk-13wk <11g/dl
2nd 14wk -26wk <10.5 3rd
27wk-40wk <10.5
postpartum <10

1unit to Blood Transfusion increases Hb by 10g/L.
Oral Ferrous supplements increase Hb by 10g/L in one week.
This is why after 36 wks BT is preferred, to have an adequate Hb level for delivery.

18
Q
Panicillin allergy patient CS 0211
which ab to give 
Tri metho   / Nitro furen
Amoxi / Co amoxi
Cefelaxime
A

DONT GIVE trimethoprim in 1st tri
DONT GIVE nitrofurantoin in 3rd tri
DONT GIVE ciprofloxacin at any time

Give Cefelaxime (10% coross reaction with penicilline but is avoidable )

19
Q

Based on plabable info Safe in pregnancy:

A

HTN: labetalol, nifedipine, hydralazine

UTI: penicillin / amoxicillin; cephalosporin / cephalexin ; erythromycin (the rest macrolids CI); clindamycin
Malaria prophylaxis: chloroquine, proguanil, mefroquine
Constipation: lactulose

CI in pregnancy: 
Trimethoprim (I trimester) 
Nitrofurantoin (near term) 
All macrolids excepting erythromycin 
Quinolone / ciprofloxacin Tetracycline / doxycycline 

Malaria prophylaxis: primaquine

20
Q

Two types of HRT

Cyclical and Continuous

A

Perimenopausal —cyclic HRT

Post menopausal … >12 months… Continues HRT

Without uterous estrogen only
With uterous if compulsion .. give IUS with estrogen only

21
Q

GY 4540 Endometrial ablation not Mirena

A
21
Q

GY 4540 Endometrial ablation not Mirena

A
22
Q

Diagnosis of PCOS CS 0040
Cannot be verified by Lab values
but usually the LHS and FSH levels will be on the BOderline maximum
and its ratio will be increased

A

the ratio of LH: FSH is more important and both may be raised.

Moreover, a diagnosis of PCOS does not depend on the levels of FSH/LH.

it depends on

  1. hirsuitism/ raised testosterone
  2. ultrasound criteria for PCOS and
  3. oligomenorrhoea or amenorrhoea
23
Q

Normally In Pregnancy
there will be Odema of hands and Proteinuria which is consider normal

BUT NICE guidlines

A

if the proteinuria is 2+= refer to obstetric urgently………… even if normotensive

if the proteinuria is 1+ and no signs for pre-eclampsia= review 1 week in the GP surgery.

24
Q

Management of Ectopic pregnancy

A

1) Signs of shock plus suspected ectopic
plus positive hcg- immediate laparotomy.

2) No signs of shock plus hcg positive plus
signs of peritonism - transvaginal
usg- if empty-
diagnostic laparoscopy.

3) no signs of shock plus hcg positive plus
no signs of peritonism-
usg- if empty-
serial hcg measurements -
if raised- diagnostic plus therapeutic laparoscopy. -
if not raised- repeat in 48 hours.

25
Q

Gestational hypertension or Pre eclampsia

Dx by PROTEIN CREATNIN RATIO

In GH Prot cret ratio <30 example 10mg/mmol

A

Protien values for the diagnosis of pre-eclampsia:
1) 24 hrs urine protien >0.3g

2) PCR >30 mg/mmol
3) ACR >8 mg/mmol

26
Q

Tubo ovarian abscess or PID

A

Lower abdominal pain + fever + abdominal tenderness WITHOUT discharge + risk factors of PID —> Possible tubo-ovarian abscess —> USG (USG could diagnose or exclude TOA quickly, swab will take time)

27
Q

OB 4170
Menopause cannot be diagnosed by FSH (but yes for pre mature ovarian failure )
its based on Clinical
If menopause + other symptoms Menorrhagia (Endometrial cancer DO USG )

A

we’re not diagnosing whether she’s menopausal or not. We’re investigating why she’s bleeding heavily at the age of 51. Hence endometrial thickness is crucial here.

28
Q

Contraception IUD or COPPER worsen menorrhagia

DVT - omit OC and Mirena and all
DVT only - Copper iud

A

patient with headace without migraine , migraine with aura , and also VTE COCP is contraindicated. Next best one is IUCD which is UKEMC1 while IUS is UKEMC 2

If it’s asking about safety, choose IUCD over IUS except with the following:

  1. Anemias
  2. Severe dysmenorrhea (ablation if Hb is very low)
  3. Endometriosis Went through the UKMEC list.
29
Q

PID suspected patient Antibiotic given
but not effective
think
Best initial investigation

A

USG

Tubo Ovarian abscess (abscess is not controlled by AB )

30
Q

Tx for Hyper emesis gravidoram OB 4210

A

hypermesis management:
FAST First:
1. Fluids

  1. Antiemetics FIRST IM THEN IV
    (First line -cyclines, Second line metroclopramide or ondansetron)
  2. Steroids (Third line) Dont give BEFORE IV ANTIEMETICS
  3. Thiamine
31
Q

Pregnancy and pain killer Junior doctor can only prescribe Paracetamol to pregnant woman.

A

NSAIDs is contraindicated after 30 weeks’ gestation

It is associated with an increased risk of premature closure of the fetal ductus arteriosus and oligohydramnios

32
Q

Types of Operation for Myoma removal
Uterus approach
Abdominal approach

A

For Intramural and subserosal —> Abdominal myomectomy

Submucosal fibroid—> hysteroscopic myomectomy

33
Q

Dont Repeat Cervical Smear in Symptomatic patient
\Cervical Smear is a Screening test
GY 2042

A

if there is abnormal bleeding that persist for > 6-8 weeks
——refer for colposcopy despite of normal cervical smear,

normal speculum examination or normal cervical swab result.

33
Q

Dont Repeat Cervical Smear in Symptomatic patient
\Cervical Smear is a Screening test
GY 2042

A

if there is abnormal bleeding that persist for > 6-8 weeks
——refer for colposcopy despite of normal cervical smear,

normal speculum examination or normal cervical swab result.

34
Q

Placenta previa
OB 2043
Bleeding after sexual intercourse
what to do next

A

To do speculum examination to look for cervical tears

SPECULUM IS SAFE
DIGITAL FINGER IS NOT SAFE

35
Q

Gynacological Swabs

A

High vaginal swab for vaginosis and trichomonas

Vulvovaginal swab for chlamydia or gonorrhea

Vulvovaginal is superior to endocervical swab

Suspected cervicitis:
Vulvovaginal swab NAATs:
1- Chlamydia +ve&raquo_space; Treat (Doxy OR Azithro)

2- Gonorrhea +ve&raquo_space; DO culture first before treating (because of resistance) To take samples for culture:
Endocervical swab in Charcoal +
High vaginal swap in Charcoal Then treat according to the sensitivity results

36
Q

GY 0020

Meigh syndrome
Benign ovarian tumor

A

Ascities and

Pleural effusion