Ovarian disease Flashcards
where do cystic follicle originate
unruptured graafian follicles or
follicles that ruptured and then sealed
What is luteal cyst lined with and what does it secrete? what happens when ruptured
luteinized granulosa cells
progesterone
peritoneal reaction
Stein-Levanthall syndrome
polycystic ovaries
Stein-Levanthall syndrome impact on insulin
insulin resistance
classification of ovarian tumors
surface epithelium
germ cells
sex cord - stroma
what is thought to give rise to epithelial neoplasia
cortical inclusions cysts
when do benign/boderline and malignant serous tumor occur
benign/boderline: younger
malignant: older
serous tumor gros presentation? bilateral or unilateral?
smooth-walled cyst
cyst with papillary excrescences
bilateral
histo for serous tumor
ciliated columnar cells
intercalted cell
is there invasion of boderline serous tumor
no
gross for malignant serous cystadenocarcinoma
more solid
invasion of ovarian stroma
histo for malignant serous cystadenoma
psammoma bodies
who gets mucinous tumors
middle age
which in more common mucinous or serous
serous
histo for mucinous benign
tall columnar cells with apical mucin
no cilia
what does benign mucinous resemble
cervix or intestines
gross for benign mucinous
multiloculated with tenacious mucous
histo for boderline mucinous tumor
complex glandular structures with nuclear atypia
what does malignant mucinous cystadenoma resemble? benign
malignant: intestinal epithelium
benign: cervical epithelium
what is pseudomyxomatous peritonei
extensive mucinous ascites
epithelial implants and adhesions
what other organ should be considered for pseudomyxomatous peritonei
appendix
what is an aggressive variant endometrioid adenocarcinoma
clear cell adenocarcinoma
what is cystadenofibroma? what is epithelium
benign fibrous stroma
- endometrioid, serous, mucinous or transitional
What is brenner Tumor
Epithelial component is transitional (bladder)
benign
