oublis Flashcards

1
Q

PD

Puissance des ABs

A

Activité antimicrobienne (CMI)
Distribution au site d’Action (PK)
Intéraction rx-bactérie

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2
Q

PD:
cinétique bactérienne au site d’infection:

qt de bact. au site sont fcts de :

A
  • effet mx sur bact
  • syst immun de l’hote sur bac
  • int. mx-syst.immun
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3
Q

PD :

impacts associés au tx antimicrobien

A
  • retard ds instauration d’un tx antimicrobien approprié
  • diminution efficacité
  • ^^ toxicité
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4
Q
QUINOLONES
1st gen
2e gend
3e gen
4e gen
A

acide nalidixique

norfloxacine, ciprofloxacine, ofloxacine

levofoxacine

moxifloxacine,gemifloxacine

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5
Q
Macrolides
t1/2vie
erythro
vs
clarithro
vs
azithro
A

1,5-3

3.5-5

11-14

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6
Q

antifongiques

puissance

poly

azo

ech

A

fogicide

surtout fongistatique

fongicide vs levures , variables vs moisissures

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7
Q

antifongiques
toxicité

poly

azo

ech

A

néphro, infusion

+++ intéractions

^ enzym hépatiques,

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8
Q

Antiviraux :

influenza :

A

virus arn sb
=> enveloppe lipidique formées de glycoprots de surface
=> 2 autres prots virales => M1 et M2

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9
Q

Pk développement

d’azi et de clari ?

A

pcq érythrom:

  • faible F
  • faible tolérance
  • dosage fréquent
  • spectre limité
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