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HEMATOLOGY 2 > OTHER TESTS FOR PRIMARY HEMOSTASIS > Flashcards

OTHER TESTS FOR PRIMARY HEMOSTASIS Flashcards

1
Q

Bleeding time test

A

Measures the length of time a wound bleeds

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2
Q

Purpose of Bleeding time

A

Detects platelet function disorders and VWD

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3
Q

Coagulation mechanism effect on Bleeding time

A

Not affected

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4
Q

Factors affecting Bleeding time

A

Platelet count/function, skin thickness/vascularity, blood vessel quality

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5
Q

Medications affecting Bleeding time

A

Aspirin (avoid 7 days), NSAIDs (24 hours before)

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6
Q

Duke method procedure

A

Finger punctured with sterile lancet, timer starts with first blood drop

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7
Q

Blotting during Duke method

A

Blot with filter paper every 30 secs, paper should not touch the wound

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8
Q

Normal bleeding time (Duke method)

A

2 to 4 minutes

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9
Q

Ivy method procedure

A

Sphygmomanometer inflated to 40 mmHg at upper forearm

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10
Q

Incision details in Ivy method

A

2 skin incisions, 2 mm deep and 2 mm long, avoiding veins

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11
Q

Blotting during Ivy method

A

Blot blood every 30 secs with filter paper (paper must not touch wound)

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12
Q

Normal bleeding time (Ivy method)

A

1 to 7 minutes

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13
Q

Modified Ivy method using a template with a standardized slit

A

Template Bleeding Time

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14
Q

Template Bleeding Time developed by

A

C.H. Mielke, Jr. and colleagues

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15
Q

Template Bleeding Time devices

A

Simplate and Surgicutt

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16
Q

Normal bleeding time (Template method)

A

2 to 9 minutes

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17
Q

Example of a capillary fragility test (tourniquet test)

A

Rumple-Leede Test

18
Q

Normal result for Rumple-Leede Test

A

Grade 1+ (0-10 petechiae); >10 or 2+ above weak capillary

19
Q

Time to check for petechiae after cuff release

A

15 minutes

20
Q

Area to check for petechiae in Rumple-Leede Test

A

1-inch diameter area on the volar surface of the arm, dorsal hands, and fingers

21
Q

Clot retraction contractile protein

A

Thrombosthenin

22
Q

Clot retraction principle

A

Normal blood clot contracts and expresses serum

23
Q

Measure of clot retraction

A

Amount of expressed serum

24
Q

Normal clot retraction requires

A

Normal fibrinogen, functioning platelets, calcium, ATP

25
Q

Normal value for Hirschboeck/Castor oil test

A

15 to 45 minutes

26
Q

Abnormal serum characteristics in Hirschboeck/Castor oil test - dark yellow

A

Jaundice

27
Q

Abnormal serum characteristics in Hirschboeck/Castor oil test - cloudy

A

Plasma cell myeloma

28
Q

Abnormal serum characteristics in Hirschboeck/Castor oil test - milky

A

Diabetes, leukemia after meals

29
Q

Normal value for MacFarlane Method

A

44-67%

30
Q

MacFarlane Method formula for Clot Retraction

A

%CR = (Amount of serum left in tube / Amount of blood used) x 100

31
Q

Abnormal clot retraction in MacFarlane Method - Thrombocytopenia

A

Inability of platelets to interact properly with fibrinogen

32
Q

Abnormal clot retraction in MacFarlane Method - Low or abnormal fibrinogen

A

Impaired clot retraction

33
Q

Abnormal clot retraction in MacFarlane Method - Paraproteinemias

A

Multiple myeloma, macroglobulinemia interfering with fibrin formation

34
Q

Abnormal clot retraction in MacFarlane Method - Glanzmann’s thrombasthenia

A

Platelet incapable of interacting with fibrin

35
Q

MacFarlane Method materials

A

5 mL fresh venous blood, glass rod, cork, calibrated tube, 37°C water bath

36
Q

MacFarlane Method observation

A

Coagulation and clot retraction, measure expressed serum

37
Q

Hirschboeck/Castor oil test materials

A

Castor oil, fresh blood, test tube

38
Q

Hirschboeck/Castor oil test observation

A

Dimpling of serum

39
Q

Rumple-Leede Test materials

A

Pressure cuff, sphygmomanometer, alcohol, sterile gauze, filter paper

40
Q

Rumple-Leede Test observation

A

Petechiae formation

HEMATOLOGY 2 (15 decks)

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