Other Intestinal Diseases Flashcards

1
Q

What is protein-losing enteropathy?

A

The term referring to intestinal conditions that lead to protein loss

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2
Q

What do protein-losing enteropathy conditions usually manifest with?

A

Hypoalbuminaemia

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3
Q

What is the most common abnormality of the GI tract?

A

Meckel’s diverticulum

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4
Q

Where is Meckel’s diverticulum usually located?

A

About 60cm from the ileocaecal valve

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5
Q

What complications can Meckel’s diverticulum cause?

A
About half contain gastric mucosa that secretes HCl, which can cause peptic ulcers which can bleed or perforate
Acute inflammation (clinically indistinguishable from acute appendicitis)
Obstruction from an associated band (rare)
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6
Q

What is management of Meckel’s diverticulum?

A

Surgical removal, often laparoscopically

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7
Q

What are the clinical features of TB affecting the intestines?

A
Abdominal pain
Weight loss
Anaemia
Fever with night sweats
Obstruction
Right iliac fossa pain
Palpable mass
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8
Q

Which area of the small intestine is most commonly affected by TB?

A

Ileocaecal area

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9
Q

What investigations are done to diagnose intestinal TB?

A

Small bowel follow through
US, MRI or CT
Histology and culture of tissue

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10
Q

How can systemic amyloidosis affect the GI tract?

A

Amyloid deposits can occur as polypoid lesions

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11
Q

What does intestinal ischaemia result from?

A

Occlusion of arterial flow, occlusion of venous outflow or failure of perfusion

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12
Q

What can cause arterial inflow obstruction?

A

Atheroma
Thrombosis
Embolism

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13
Q

Which patients tend to have venous outflow occlusion?

A

Sick patients with circulatory failure

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14
Q

What can cause intestinal infarction without occlusion?

A

Reduced cardiac output, hypotension and shock, all causing reduced intestinal blood flow

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15
Q

What is the most common cause of acute small intestinal ischaemia?

A

Embolus from the heart

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16
Q

How do patients present with acute small intestinal ischaemia?

A

Sudden abdominal pain and vomiting, with a distended and tender abdomen and absent bowel sounds

17
Q

What is chronic small intestinal ischaemia usually caused by?

A

Atheromatous occlusion or cholesterol emboli of the mesenteric vessels

18
Q

What is the characteristic symptom of chronic small intestinal ischaemia?

A

Postprandial abdominal pain and weight loss

19
Q

How is chronic small intestinal ischaemia dignosed?

A

Angiography

20
Q

What is eosinophilic gastroenteritis?

A

Eosinophilic infiltration and oedema of any part of the GI mucosa

21
Q

How is diagnosis of eosinophilic gastritis made?

A

Endoscopic biopsy

22
Q

How is eosinophilic gastroenteritis treated?

A

Corticosteroids, particularly if peripheral oedema is present

23
Q

What is lymphangiectasia?

A

Dilation of the lymphatics

24
Q

What is the main feature of intestinal lymphangioectasia?

A

Hypopoteinaemia

25
Q

How is intestinal lymphangiectasia diagnosed?

A

Capsule endoscopy

Serology

26
Q

How is intestinal lymphangiectasia managed?

A

Low-fat diet, fat-soluble vitamin supplements

Octreotide is used in primary cases

27
Q

What is abetalipoproteinemia?

A

Rare congenital disorder that means chylomicrons are not formed

28
Q

What are the clinical features of abetalipoproteinemia?

A

Anacthocytosis (spiky red cells owing to membrane abnormalities)
A form of retinitis pigmentosa
Mental and neurological abnormalities