Colon and Rectum Flashcards
What are the parts of the large colon?
Ascending, transverse, descending, sigmoid
What are the teniae coli?
Three bands that complete the longitudinal muscle layer.
They produce the haustral pattern
Describe the mucosa of the large intestine
Mucosa is lined with epithelial cells and goblet cells.
There are crypts but no villi so the surface is flat
Which muscles are contracted and relaxed in defecation?
Diaphragm and abdominal muscles are contracted
Pelvic floor and anal sphincter are relaxed
Which GI diseases can cause constipation?
Intestinal obstruction and pseudo-obstruction
Colonic disease (e.g. carcinoma, diverticula)
Aganglionitis (Hirschsprung’s, Chaga’s)
Painful anal conditions (e.g. fissures)
What investigation is indicated when there has been a recent change in bowel habit in association with other significant symptoms?
Colonoscopy or CT
What are the three categories of constipation, and which is the most common?
Normal transit time (most common)
Defecatory disorders
Slow transit
What is normal transit constipation?
Stool frequency is normal but people believe they have constipation due to passage of hard stools
Patients may have abdominal pain or bleeding
What investigation distinguished between normal and slow transit constipation?
Marker studies of colonic transit
What is defecatory disorder induced constipation?
Where contraction rather than relaxation of the puborectalis and external anal sphincter may prevent evacuation
What is the most common cause of a defecatory disorder?
Dysfunction of the anal sphincter and pelvic floor
Who predominantly experiences slow transit constipation?
Young women with infrequent bowel movements
What are the symptoms of slow transit constipation?
Infrequent urge to defecate
Bloating
Abdominal pain and discomfort
What treatment measure should be taken in normal and slow transit constipation?
Increase in fibre in the diet and increased fluid intake
What are examples of bulk-forming laxatives?
Dietary fibre
Methylcellulose
Sterculia
Ispaghula husk
What are some examples of stimulant laxatives?
Senna Glycerol suppository Bisacodyl Docusate sodium Sodium picosulphate
What are some examples of osmotic laxatives?
Lactulose
Macrogols
Phosphate enema
Citrate enema
How do stimulant laxatives work?
By stimulating motility and intestinal secretion
How do osmotic laxatives work?
By increasing fluids and electrolytes which stimulates contraction
Which type of laxatives are preferred?
Osmotic
What is megacolon?
A term for conditions where the colon is dilated
What can megacolon be secondary to?
Chronic constipation
Chaga’s disease
Which condition should be excluded in megacolon, and what is this condition?
Hirschsprung’s disease
An aganglionic section of the rectum causes constipation and subacute obstruction
What is minor and major incontinence?
Minor: inability to control flatus and liquid stool, causing soiling
Major: frequent and inadvertent evacuation of stool of normal consistency
What are some causes of incontinence?
Congenital abnormalities Anal sphincter dysfunction Rectal prolapse Faecal impaction with overflow diarrhoea Severe diarrhoea Neurological and psychological disorders
What are causes of anal sphincter dysfunction?
Structural damage
Pudendal nerve damage
Perianal descend
What us the initial medical management for incontinence?
Loperamide
What is ischaemic colitis caused by?
Occlusion of branches of the superior or inferior mesenteric artery