Other Drugs

Question 1

Adenosine

Answer 1

Used in arythmias esp. SVT
DOA is 15 secs
Can work by blocking Ca influx and increasing K efflux causing slowed conduction at the AV node (given chance to SA node to work)
Not used with theophylline or caffeine cause they can blunt its effect

S/E flushing, bronchoconstriction, hypotension, sense of impending doom chest pain

Question 2

Benzonatate

Answer 2

Antitussive

Question 3

Tear gas

Answer 3

Lacrimating agent used as chemical threat
Choracetophenone or phenacyl chloride

Question 4

Adamsite

Answer 4

Vomititing agent used to control riot

Question 5

Acamprostate

Answer 5

Used in alcohol abstinence
Mechanism not fully known but act on glutamate neurotransmitters system to balance excitation and inhibition

Question 6

Disulfiram

Answer 6

Alcohol withdrawal
Reacts with ethanol to increase serum acetaldehyde conc which has unpleasant symptoms
Inhibits aldehyde dehydrogenase

Question 7

Hydroxyzine

Answer 7

Antihistamine used for itching caused by allergies and anxiety

Can cause sedation

Question 8

Allopurinol

Answer 8

Xanthine oxidase inhibitors
Which is used in the prevention of gout

Question 9

Allupuronol

Answer 9

Xanthine oxidase inhibitors
Which

Question 10

Naloxegol

Answer 10

Peripherally acting opioid receptor antagonists used in treating opioid induced constipation. Developed by AstraZeneca in 2014

Question 11

Misoprostol

Answer 11

This is an eicosanoid from arachidonic acid
It’s a PGE1 analogue

Question 12

Latanoprost

Answer 12

Similar in structure to misoprostol (has ketone) but has hydroxyl
It’s a PGF2alpha analogue