Other Drugs Flashcards
Adenosine
Used in arythmias esp. SVT
DOA is 15 secs
Can work by blocking Ca influx and increasing K efflux causing slowed conduction at the AV node (given chance to SA node to work)
Not used with theophylline or caffeine cause they can blunt its effect
S/E flushing, bronchoconstriction, hypotension, sense of impending doom chest pain
Benzonatate
Antitussive
Tear gas
Lacrimating agent used as chemical threat
Choracetophenone or phenacyl chloride
Adamsite
Vomititing agent used to control riot
Acamprostate
Used in alcohol abstinence
Mechanism not fully known but act on glutamate neurotransmitters system to balance excitation and inhibition
Disulfiram
Alcohol withdrawal
Reacts with ethanol to increase serum acetaldehyde conc which has unpleasant symptoms
Inhibits aldehyde dehydrogenase
Drugs that can cause disulfiram like reactions: metronidazole, cephalosporins, chlorpropamide, lopinavir + ritonavir (has alcohol)
Hydroxyzine
Antihistamine used for itching caused by allergies and anxiety
Can cause sedation
Allopurinol
Xanthine oxidase inhibitors
Which is used in the prevention of gout
Allupuronol
Xanthine oxidase inhibitors
Which
Naloxegol
Peripherally acting opioid receptor antagonists used in treating opioid induced constipation. Developed by AstraZeneca in 2014
Misoprostol
This is an eicosanoid from arachidonic acid
It’s a PGE1 analogue
Latanoprost
Similar in structure to misoprostol (has ketone) but has hydroxyl
It’s a PGF2alpha analogue
Ursodiol
Natural bile acid found in humans used for biliary cirrhosis
K PHOS
Potassium acid phosphate, it is a urinary acidifier and increases anti bacterial effect of methenamine by enhancing its conversion to formaldehyde in acidic urine
Mafenide
Topical agent used in burns
