Obesity

Question 1

Phendimetazine

Answer 1

Appetite suppressant
Sympathomimetic acts on hypothalamus to activate fight or flight wch leads to more energy expenditure with less appetite
It is a prodrug converted to phenmetrazine
Acts on dopamine and serotonin also, improves mood and used for short time due to tolerance and abuse potential

Question 2

Orlistat

Answer 2

Bile lipase inhibitor
Inhibits absorption of 30% TG(wch is broken down to glycerol and FA)
Best used with exercise and diet modification