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Systemic Pharm > Osteoporosis > Flashcards

Osteoporosis Flashcards

1
Q

What are the possible iatrogenic causes of osteoporosis?

A 
Steroids
Anti-epileptics
Anticoagulants
PPI's
TZD's
Lithium
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2
Q

What type of drug is Alendronate?

A

Nitrogenous Bisphosphonate

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3
Q

What are the 3 serious adverse effects of Alendronate?

A

Angioedema
Uveitis
Scleritis

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4
Q

What is the MOA of Alendronate?

A

Affinity for Co2, it accumulates in bone, is ingested by osteoclasts, it kills them by inhibiting HMG-CoA reductase, and reduces bone resporption

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5
Q

What are the indications for Alendronate?

A

Osteoporosis

Paget’s Bone disease

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Systemic Pharm (15 decks)

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