Anti-Rheumatics Flashcards
What may happen when HCQ and Botox interact?
Impaired Botox activity
What are the 3 indications for HCQ?
Rheumatoid Arthritis Systemic Lupus Erythematosus Malaria prophylaxis
Name 3 DMARDs
Hydroxycholorquine (HCQ) Chloroquine Methotrexate
HCQ can inhibit activity of which drug?
Botox
What is the potential hypersensitivity to HCQ?
Angioedema
What is the MOA of HCQ?
Inhibits rheumatoid factor and acute phase reactants
Interrupts parasitic vesicle functions and phospholipid metabolism by increasing pH
What is the contraindication of HCQ?
Retinal or visual changes
What are the serious ocular adverse effects of HCQ?
Retinopathy
Vision changes
Which is more toxic, HCQ or Chloroquine?
Chlolorquine
What are the 2 common adverse effects of HCQ?
Headache
Photosensitivity
HCQ dosing of over ___g per day places the eyes at great risk for retinal toxicity.
1000g
What effects can HCQ have on the cornea?
Verticillata
Vortex keratopathy
