Ortho / Rheum Flashcards
Which STI is most likely to lead to reactive arthritis?
- chlamydia
- gonorrhoea
Chlamydia
Which STI is most likely to lead to septic arthritis?
- chlamydia
- gonorrhoea
Gonorrhoea
Can’t see, pee or climb a tree makes you think of what condition
Reactive arthritis
inability to dorsiflex the foot after a blow to the knee
Which nerve is likely to be injured?
Common peroneal nerve
Foot drop.
Which nerve is likely to be injured?
Common peroneal nerve
Which nerve supplies the serratus anterior?
Long thoracic nerve
Which cranial nerves are present in the cerebellopontine angle?
V, VII, VIII
60 year old woman walks with a drop foot and a high stepping gait shortly after a hip replacement. Which nerve is responsible for this?
- femoral
- sciatic
Sciatic nerve
A broad based unstable gait with veering to the right side.
Cerebellar disease
34 year old woman falls to the ground after hearing some bad news suggests a vasovagal syncope. True or false>
True
First line DMARD in RA?
Methotrexate
How is disease activity in RA measured?
DAS 28 score
- score > 5.1 then eligible for biologic therapy
DMARDs are useful in ankylosing spondylitis. True or false?
False
- not useful in spinal disease
RA is usually symmetrical. True or false?
True
Psoriatic arthritis is usually symmetrical / asymmetrical ?
Asymmetrical
Reactive arthritis mainly affects large / small joints?
Large joints
- commonly the knee
- presents few weeks after illness
In SLE there is low complement / raised complement?
Low complement
How does systemic sclerosis come around?
Excess collagen deposition in the skin
Which medication is used to manage raynauds phenomenon?
CCB
Anti phospholipid syndrome
- prolonged PT / APTT
APTT
Lupus anticoagulant +ve
Anticardiolipin +ve makes you think
Anti phospholipid syndrome
Patients who are found to have positive antibodies for anti-phospholipid syndrome but who have never had had an episode of thrombosis do not require anti-coagulation. True or false?
True
Gout - synovial fluid sample shows
Needle shaped monosodium urate crystals
Negative bifringence
Polymyalgia rheumatica - use high dose / low dose steroids?
Low dose steroids (15mg)
Constant headache, visual disturbances, jaw claudication and scalp tenderness suggests
GCA
Typical biopsy findings include mononuclear infiltration or granulomatous inflammation, usually with multinucleated giant cells.
This suggests which condition
GCA
Which dose of steroids should you use for GCA?
40-60mg
What does this suggest?
symmetrical, proximal muscle weakness in the upper and lower extremities. This is often insidious in onset and is commonly noticed as difficulty with particular activities e.g. climbing stairs
Anti-Jo-1 +ve
Polymyositis
What does this suggest?
symmetrical, proximal muscle weakness in the upper and lower extremities. This is often insidious in onset and is commonly noticed as difficulty with particular activities e.g. climbing stairs
+ heliotrope rash
+ gottrons papules on fingers
Dermatomyositis
Name 2 large cell vasculitis
GCA
Takayasu arteritis
Takayasu arteritis commonly affects young / old woman?
Young (2nd / 3rd decade of life)
Mainstay of treatment for takayasu arteritis
40-60mg prednisolone
nose bleeds, deafness, recurrent sinusitis and nasal crusting (over time there can be collapse of the nose). Respiratory symptoms such as haemoptysis and cavitating lesions on x-ray are frequently seen. What does this suggest? - EGPA - GPA - MPA
GPA
late onset asthma, rhinitis and a raised peripheral blood eosinophil count. Neurological symptoms such as mono neuritis multiplex are common. What does this suggest? - EGPA - GPA - MPA
EGPA
Child
URTI few weeks ago
Now has vasculitis type non blanching rash. purpuric rash over the buttocks and lower limbs, abdominal pain and vomiting and joint pain.
What is likely diagnosis?
HSP
- IgA mediated
What is the management of HSP
Usually self limiting
Which of these autoantibodies is most specific for SLE?
a. Anti-Scl-70
b. Anti-nuclear antibody
c. Anti-Ro antibody
d. Anti-DNA binding antibody
e. Anti-smooth muscle antibody
d. Anti-DSDNA
Which of these tests is the initial investigation of choice for detecting renal involvement in vasculitis?
a. Urea
b. Glomerular filtration rate (GFR)
c. Urinalysis
d. Creatinine
e. Renal ultrasound scan
c. urinalysis
If allopurinol cant be tolerated, which drug is used instead?
Febuxostat
Pain, weakness, wasting - is this a joint problem or is this a muscle problem?
Muscle problem
what duration is prolonged early morning stiffness?
over 1 hour
Inflammatory conditions have had a shorter/longer duration of onset?
Shorter
DIP joint involvement - think which type of arthritis?
OA
won’t be RA
Base of thumb involved - which type of arthritis?
Osteoarthritis
‘squaring of the thumb’
Why are the DIP joints not involved in rheumatoid arthritis?
Only a little amount of synovial fluid in DIP joints
Over 50, acute onset pain in shoulder girdle and hip girdle.
Polymyalgia rheumatica
Whats the most common organism to cause reactive arthritis?
Campylobacter
also chlamydia if STI
Which medications can precipitate gout?
Thiazide like diuretics
Which medications can precipitate gout?
Thiazide like diuretics
Have you ever been to the eye clinic as an emergency. Why is this important in rheumatology?
Uveitis - think about seronegative arthropathies
Butterfly malar rash is made worse by
Sun
- it is photosensitive
takes a while to go away
Raynauds that develops later on in life. What disease does this suggest?
Systemic sclerosis
Bilateral carpal tunnel syndrome. What should you be wary of?
Rheumatioid arthritis
50 year old woman develops raynauds and dysphagia?
Systemic sclerosis
low trauma fractures and family history of osteoporosis. What is the best investigation?
bone density scan
Bilateral hilar lymphadenopathy
erythema nodosum
fever
This is the triad of
Sarcoidosis
Approach to acute monoarthritis. What investigations must you do?
Joint aspirate
Blood tests: FBC, CRP, blood cultures, serum uric acid
X-rays
Patient with gout like symtoms but normal serum uric acid levels. What should you do>
Treat for gout and re-check serum uric acid levels in a few weeks
Where are heberdens nodes?
What condition is this seen in?
DIP joints
OA
Onycholisis and nail pitting and dactylitis is common in which condition?
Psoriatic arthritis
Age between 20 and 40. Lasting longer than 12 weeks. Worse in the morning ,improving with exercise. Buttock pain Relief with NSAIDs Night time awakening. These patients get investigated for?
Ankylosing spondylitis
Should you always x-ray both hands and feet in ?RA even if the patient doesn’t have any problems with the feet? or just do hands?
Do both Hands and feet x-ray
First line DMARD in Rheumatoid arthritis
methotrexate
How long do DMARDs take to work roughly?
What are used in the interm?
3 months
Steroids are used in the interim as DMARDs take months to work
What can methotrexate do in the lungs?
Pulmonary pneumonitis
How is methotrexate given in the treatment of rheumatoid arthritis?
It is given as a weekly dose followed by folic acid at least 24 hours later.
Hydroxychloroquine is never used on its own. True or false?
True
What is the first line treatment in gout?
NSAIDs
- can use colchicine if NSAIDs don’t work but this carries risk of diarrhoea
What is the management of compartment syndrome?
Emergency fasciotomy
Management of hypertrophic non union fracture
Plate and screws to stabilise
What are the 3 x-ray views for assessing c-spine fracture
AP
Lateral
Peg open mouth
When thinking of pelvic fractures, what analogy do you think of?
Polomint
- if break in one place there is most likely going to be another break elsewhere
‘open book pelvic fracture’. how does this occur and what is the management
Occurs due to anterior-posterior compression injury whereby the pubic symphisus is disrupted
Tx:
Initial reduction -> pelvic binder -> external fixation
shortening of the affected limb, leg flops into external rotation, can’t straight leg raise
this makes you think
NOF fracture
What is the main complication of NOF fracture to be aware of?
avascular necrosis
Which carries more risk for AVN:
- intracapsular NOF fracture
- extracapsular NOF fracture
Intracapsular NOF fracture
- in the capsule so risk of disrupting blood supply to femoral head
Management of intracapsular NOF fracture
Hip replacement
- total
- partial
Management of extracapsular (intertrochanteric) NOF fracture
Internal fixation
- hip screw
- IM nail
Management of extracapsular (subtrochanteric) NOF fracture
Thomas splint + analgesia -> IM nail
Which nerve is most likely to be damaged in humeral shaft fracture?
Radial nerve
Wrist drop
Loss of sensation in first dorsal web space
This suggests injury to which nerve?
Radial nerve
Define colles fracture
Extra-articular fracture of the distal radius
Which nerve is at risk of damage in a colles fracture
median nerve
Smiths fracture has volar/dorsal displacement
Volar displacement
- occurs after falling onto flexed wrist
Pain in the anatomical snuff box following FOOSH may indiacte?
Scaphoid fracture
What is the major complication to be aware of for scaphoid fracture?
Avascular necrosis
Management of stable ankle fracture
Moonboot / cast for 6 weeks
Management of unstable ankle fracture
Open reduction + internal fixation
Monteggia fracture is fracture of the radius / ulna?
Fracture of ULNA with dislocation of the radial head
Galeazzi fracture-dislocations is fracture of the radius / ulna?
Fracture of the RADIUS with dislocation of the ulna