Antibiotic man Flashcards
Gram -ve coliforms. Which antibiotic is commonly used?
Gentamicin
Pseudomonas aeruginosa organism is resistant to many antibiotics. Which antibiotic is used?
Ciprofloxacin
ESBLs (extended spectrum beta lactamase) are mainly sensitive/resistant to most penicillins?
Resistant
Anaerobic organism. Which antibiotic is commonly used?
Metronidazole
Anaerobes are generally sensitive to which antibiotics
Mainly metronidazole
Also
- co-amoxiclav
- clindamycin
- pip-tazobactam
- meropenem
MRSA is sensitive to which antibiotic?
Vancomycin
Bacterial meningitis - which antibootic is used (incl dose)
IV Ceftriaxone 2g bd
Along with antibiotic therapy, what is used to tread bacterial meningitis
IV dexamethasone 10mg qds
What is the treatment of bacterial meningitis in pt over 60 years old and likely organism is listeria?
IV ceftriaxone 2g bd +
IV dexamethasone 10mg qds +
IV amoxicillin 2g 4 hourly
What is the treatment for suspected encephalitis?
IV aciclovir
Pneumococci are sensitive/resistant to penicillin?
Sensitive
Meningococci are resistant/sensitive to penicillin ?
Sensitive
Listeria is sensitive/resistant to amoxicillin
Sensitive
Herpes simplex virus is sensitive to which viral drug
IV aciclovir
Common causative organism for epiglottitis?
Haemophilus influenza
Strep
Common causative organism for tonsillitis
Group A streptococcus
Beta haemolytic streptococci are sensitive/resistant to penicillin
Sensitive
Epiglottitis management
IV ceftriaxone 2g od
Mild/moderate CAP causative organisms
Strep pneumonia
Haemophilus influenzae
Mycoplasma pneumonia
Severe CAP causative organisms
Same as mild/moderate: Strep pneumoniae, haemophilus influenzae Plus Coliforms Atypicals
Post flu pneumonia is classically caused by which organism
Staph aureus
Common causative organisms for acute exacerbation of COPD
Pneumococcus
Haemophilus influenzae
Common causative organisms of HAP
Strep pneumonia
Haemophilus influenzae
Coliforms
Most haemophilus influenzae are sensitive to amoxicillin. True or false?
True
CAP curb score of 0-2 treatment (incl dose and duration)
Amoxicillin 1g tds for 5 days
If penicillin allergic use doxycycline
CAP severe 3-5 CURB score then what is the management
IV Co amoxiclav + P.O. doxycycline
Step down to P.O. doxycycline
If penicillin allergy then monotherapy of IV levofloxacin
Severe CAP but patient is NBM. What is the treatment?
IV co-amoxiclav + IV clarithromycin
Non severe HAP management
P.O. amoxicillin for 5days
Doxycycline if penicillin allergic
Severe HAP management
IV amoxicillin + IV gentamicin
Step down to P.O. co-trimoxazole
Total 7 days
Aspiration pneumonia non severe management
P.O. amoxicillin + metronidazole for 5 days
Severe aspiration pneumonia management
IV amoxicillin + metronidazole + gentamicin
Step down to P.O. amoxicillin + metronidazole
Total 7 days
What is first line d treatment of acute exacerbation of COPD
Amoxicillin P.O. 5 days
What is second line treatment for acute exacerbation of COPD
Doxycycline P.O. for 5 days
Endocarditis - Native valve acute - what is likely causative organism
Staph aureus
Endocarditis - native valve sub acute - what is the most likely organism
Strep viridans
Prosthetic valve endocarditis what is likely causative organism
Staph epidermidis
Native valve acute endocarditis management
IV flucloxacillin 2g 6 hourly
Native valve subacute endocarditis management
IV amoxicillin + IV gentamicin
Prosthetic valve endocarditis management
IV vancomycin + IV gentamicin
After 3-5 days add in rifampicin P.O.
E. coli 0157 is most common in adults or children?
Children
C diff non severe management
P.O. metronidazole for 10 days
C diff severe management
P.O. vancomycin +/- metronidazole for 10days
Peritonitis management
IV amoxicillin c metronidazole + gentamicin
For 7 days
Uncomplicated lower UTI common organisms (2)
Coliforms
Enterococcus
Complicated UTI investigation
Urinalysis - MSU - white bottle
Urine culture
Blood cultures
Catheter associated UTI - investigation
Blood culture
Uncomplicated female lower UTI management
P.O. Trimethoprim or nitrofurantoin for 3 days
Uncatheterised male lower UTI management
P.O. Nitrofurantoin or trimethoprim for 7 days
Complicated lower UTI (both male and female) in gp setting management
Co-amoxiclav or co-trimoxazole for 14 days
Complicated upper UTI (pyelonephritis) management
IV amoxicillin + gentamicin
Step down to P.O. co-trimoxazole
Total 7 days
Catheterised patient UTI management
IV amoxicillin+ gentamicin
Step down to P.O. co-trimoxazole
Total 7 days
Common causative organism for cellulitis
Staph aureus
Diabetic foot infection. What is the most likely causative organism?
Staph aureus
Management of cellulitis
IV flucloxacillin
Management of diabetic foot infection
Flucloxacillin for 7 days
Which antibiotics are used in sepsis 6
IV amoxicillin + metronidazole + gentamicin
