Organelles

Question 1

What is the first step in vesicular transport?

Answer 1

Question 2

Describe golgi complex structure

Answer 2

Question 3

What is the function of the golgi complex

Answer 3

Question 4

What are the dynamics of transport through golgi complex

Answer 4

Question 5

What are coated vesicles

Answer 5

Question 6

What are coat proteins

Answer 6

Question 7

Describe COPII-coated vesicles

Answer 7

Question 8

Describe the structure of transport vesicles

Answer 8

Question 9

Describe the mechanisms that maintain unique membrane compositions

Answer 9

Question 10

Explain how lysosomal enzymes act as sorting proteins at the trans golgi network (TNS)

Answer 10

Question 11

How do non-lysosomal enzymes sort proteins at the TNS

Answer 11

Question 12

How are vesicles targeted to a particular compartment

Answer 12

1. Movement of vesicle toward specific target compartment
   -Microtubules, motor proteins
2. Tethering vesicles to target compartment
   -Mediated by diverse collection of ‘tethering’ proteins
3. Docking vesicles to target compartment
   -Close contact of membranes via interaction integral proteins
4. Fusion

Question 13

Explaing targeting vesicles in neurons

Answer 13

Question 14

What is exocytosis

Answer 14

-Discharge of secretory vesicle/granule after fusion with plasma membrane
-Triggered by increase in calcium
-Contact between vesicle and plasma membrane = fusion pore
-Vesicle membrane: luminal part = extracellular surface of plasma membrane, cytosolic part = intracellular surface