Oncology

Question 0

t 15:17

Answer 0

APML (acute promyelocytic leukemia)

Treat with trans-retinoic acid + chemo

Question 1

Aeur rods

Answer 1

AML

Question 2

Most common cause of isolated splenomegaly

Answer 2

CML

Question 3

t 9:22 or BCR-Abl fusion gene present in every single cell

Answer 3

CML

Question 4

Starry sky histology

Answer 4

Burkitt’s lymphoma

Question 5

t 8:14

Answer 5

Burkitt’s Lymphoma

Question 6

Highest incidence of tumor lysis syndrome

Answer 6

Burkitt’s lymphoma

Question 7

Cancer associated with intussusception

Answer 7

Burkitt’s Lymphoma

Question 8

Cancer associated with EBV

Answer 8

African Burkitt’s

Question 9

LAD above the diaphragm

Answer 9

Lymphoblastic lymphoma

Question 10

LAD below the diaphragm

Answer 10

Burkitt’s

Question 11

Reed-Sternberg cells

Answer 11

Hodgkin’s Disease

Question 12

Opsoclonus myoclonus

Answer 12

Neuroblastoma

Question 13

Periorbital eechymoses

Answer 13

Neuroblastoma

Question 14

Increased urine catecholamines (vanillymandelic acid, homovanillic acid)

Answer 14

Neuroblastoma

Question 15

Bluish nodular skin rash

Answer 15

Stage 4S Neuroblastoma. “Blueberry muffin rash”

Question 16

Hemihypertrophy and aniridia

Answer 16

Wilm’s Tumor

Question 17

Associated with Neurofibromatosis and Beckwith Wiedeman Syndrome

Answer 17

Wilm’s Tumor

Question 18

Unilateral leukocoria in 18 month old

Answer 18

Retinoblastoma

Question 19

13q- deletion of Rb tumor suppressor gene

Answer 19

Retinoblastoma

Question 20

Painless lesion/ firm mass at left proximal tibia in adolescent male

Answer 20

Osteogenic Sarcoma

Question 21

Codman’s Triangle

Answer 21

Ostegenic Sarcoma

Question 22

Sunburst pattern on X-ray

Answer 22

Osteogenic Sarcoma

Question 23

Painful bony lesion in MID bone

Answer 23

Ewing’s Sarcoma

Question 24

t 11:22

Answer 24

Ewing Sarcoma

Question 25

Present with signs of increased ICP

Answer 25

Medulloblastoma and Astrocytoma

Question 26

Ataxia, CN palsies (VI), head tilt, diplopia

Answer 26

Brainstem Glioma

Question 27

DI, holes in skull, rash

Answer 27

Langerhans Cell Histiocytosis

Question 28

Birbeck granules, T6 antigen staining

Answer 28

Histiocytosis

Question 29

MYC-N oncogene is poor prognostic indicator

Answer 29

Neuroblastoma

Question 30

Most common NON CNS solid tumor of children

Answer 30

Neuroblastoma

Question 31

Mom finds mass in bathtub

Answer 31

Wilm's Tumor

Question 32

Wilm's tumor, aniridia, GI problems, MR

Answer 32

WAGR

Question 33

Cancer associated with p53 Li Fraumeni syndrome

Answer 33

Rhabdomyosarcoma

Question 34

Bitemporal heminopsia

Answer 34

Craniopharygioma

Question 35

Optic Glioma

Answer 35

NF type 1

Question 36

Vestibular schwannoma

Answer 36

NF type 2

Question 37

Giant cell tumor

Answer 37

Tuberous sclerosis

Question 38

Syndrome associated with hemangiomas

Answer 38

Von Hippel Lindau