Oncology Flashcards
Neutropenic sepsis Mx
Immediate iv broad spectrum antibiotics
To what regional lymph nodes is ovarian ca most likely to spread to initially?
Para-aortic nodes
Superior vena cava obstruction in advanced lung ca 1) features, 2) mx
1) SOB, progressive headache, swollen face + neck, distended veins on chest
2) Dexamethasone to reduce tumour swelling
What does needle biopsy of a carcinoma show?
Nuclei that are
- Enlarged
- Hyperchromatic
- Pleomorphic
What is the most likely route of tumour spreading when +ve for thyroid transcription factor-1?
Haematogenous
Bony mets v osteosarcoma
Bony mets
- Systemic syx
- XR: lytic/sclerotic lesions
Osteosarcoma
- Localised bone pain/swelling/tenderness
- XR: destructive lesion w sunburst appearance; often in metaphysis of long bone
What is this?
Bony mets
What is this?
Osteosarcoma
Which virus is associated with SCC of the oropharynx?
HPV
What will colonoscopy show for precancerous changes which increase risk of developing colorectal ca? + Mx
Multiple polyps with adenomatous change & low grade dysplasia
+ panproctocolectomy (complete removal of colon, rectum & anus)
HCC ca marker
alpha-fetoprotein
Tumour lysis syndrome features
- Recent chemo
- Development of AKI
Which ix confirms TLS?
Serum urate
(due to release of purines from Ca cells -> metab to uric acid)
Most effective analgesia for mod-severe ca pain
Morphine sulfate continuous SC infusion
Initial trx for brain mets
Dexamethasone
