Infx Diseases

Question 1

Epstein-Barr virus/ glandular fever / infectious mononucleosis features

Answer 1

• Fever
• Sore throat
• Fatigue
• Lymphadenopathy
• Palatal petechiae
  Often younger person

Question 2

Which form of malaria most likely when there is cerebral involvement? (E.g., drowsiness/confusion)

Answer 2

Plasmodium falciparum

Question 3

Lymphogranuloma venereum (LGV) features

Answer 3

• Painful swelling in groin
• Pain on BO (perinatal ulcer)
• Commonly in MSM + unprotected encounter

Question 4

Antibx of choice if MRSA

Answer 4

Vancomycin

Question 5

HIV seroconversion features

Answer 5

• Maculopapular rash
• Sore throat
• Fever
• Lymphadenopathy
• Splenomegaly
• Low WCC
• Low platelets

Question 6

How does genital warts present?

Answer 6

• Caused by HPV
• Small, flesh-coloured, or grey bunps in genitals or anus
• May be single or cluster
• Usually painless
• May take weeks-months to appear

Question 7

How does herpes simplex present?

Answer 7

• Small, fluid-filled blisters on genitals/anus/or mouth
• Typically in clusters
• Usually painful
• Present within days- weels
  (No cure)

Question 8

How does syphilis present?

Answer 8

(- Teponema pallidum)
- 1: single chancre within few weeks
- 2: rash across body + flu-like syx
-3: latent
- 4: tertiary - organ systems

Question 9

Mx for gonorrhoea

Answer 9

Ceftriaxone (and azithro)

Question 10

Mx for chlamydia

Answer 10

Azithromycin

Question 11

Most likely cause of bloody diarrhoea after BBQ 5 days ago

Answer 11

Campylobacter jejuni

Question 12

Mx for BV

Answer 12

PO Metronidazole

Question 13

LGV mx

Answer 13

Doxycycline

Question 14

Which are the following
1. Gram +ve diplococci
2. Gram -ve diplococci
3. Gram +ve cocci in clusters
4. Gram +ve bacilli
5. Gram -ve bacilli

Answer 14

1. Strep pneumoniae
2. Neisseria meningitidis
3. Staph aureus
4. Listeria monocytogenes or clostridium perfringens
5. E coli/ klebsiella

Question 15

Acute worsening of infx after starting ART

Answer 15

IRIS (immune reconstitution inflammatory syndrome)

Question 16

Brain MRI + ring enhancing lesions

Answer 16

toxoplasmosis encephalitis

Question 17

Plaques + HHV 8

Answer 17

Kaposi’s sarcoma

Question 18

?HIV ix

Answer 18

HIV abs and p24 antigen
- If -ve, repeat in 12 weeks

Question 19

At what CD4 count is it considered AIDS

Answer 19

<200 CD4

Question 20

CHancroid/ haemophilus ducreyi mx

Answer 20

PO azithromycin

Question 21

Painful genital ulcers + lymphadenopathy

Answer 21

Chancroid / haemophilus ducreyi

Question 22

Syphilis ix

Answer 22

Lesion present = dark field microscopy from lesion
- If +ve: coiled spirochaete bacterium w corkscrew appearance

If no lesion = treponema serological testing <+ve in both active AND past infx>

Question 23

Syphilis mx

Answer 23

IM benzathine benzylpenicillin

if neurosyphilis -> IV aqueous benzylpenicillin

Question 24

HIV + seizures + MRI showing demyelination

Answer 24

Progressive multifocal leukoencephalopathy

Question 25

Crypotococcal meningitis mx

Answer 25

Amphotericin B and Flucytosine

Question 26

C diff mx

Answer 26

PO Vancomycin

Question 27

Steatorrhoea + travel abroad

Answer 27

Giardia

Question 28

Stool watery and then bloody - traveled to africa or asia

Answer 28

Shigella

Question 29

Salmonella v campylobacter incubation period

Answer 29

Salmonella 8-72h
Campy 1-7 days

Question 30

Thick v thin film for malaria ix

Answer 30

Thick = diagnose
Thin = subtype

Question 31

Bulls eye rash (erythema chronicum migrans)

Answer 31

Lyme disease

Question 32

Retro-orbital pain, myalgia, and rash

Answer 32

Dengue

Question 33

Relative brady + rose spots

Answer 33

Salmonella typhi

Question 34

Ix for infx mononucleosis (epstein barr)

Answer 34

monospot blood test

Question 35

Malaria mx

Answer 35

Artemisinin combo therapy

Question 36

Which malaria is severe TM

Answer 36

P. falciparum