Infx Diseases Flashcards
Epstein-Barr virus/ glandular fever / infectious mononucleosis features
- Fever
- Sore throat
- Fatigue
- Lymphadenopathy
- Palatal petechiae
Often younger person
Which form of malaria most likely when there is cerebral involvement? (E.g., drowsiness/confusion)
Plasmodium falciparum
Lymphogranuloma venereum (LGV) features
- Painful swelling in groin
- Pain on BO (perinatal ulcer)
- Commonly in MSM + unprotected encounter
Antibx of choice if MRSA
Vancomycin
HIV seroconversion features
- Maculopapular rash
- Sore throat
- Fever
- Lymphadenopathy
- Splenomegaly
- Low WCC
- Low platelets
How does genital warts present?
- Caused by HPV
- Small, flesh-coloured, or grey bunps in genitals or anus
- May be single or cluster
- Usually painless
- May take weeks-months to appear
How does herpes simplex present?
- Small, fluid-filled blisters on genitals/anus/or mouth
- Typically in clusters
- Usually painful
- Present within days- weels
(No cure)
How does syphilis present?
(- Teponema pallidum)
- 1: single chancre within few weeks
- 2: rash across body + flu-like syx
-3: latent
- 4: tertiary - organ systems
Mx for gonorrhoea
Ceftriaxone (and azithro)
Mx for chlamydia
Azithromycin
Most likely cause of bloody diarrhoea after BBQ 5 days ago
Campylobacter jejuni
Mx for BV
PO Metronidazole
LGV mx
Doxycycline
Which are the following
1. Gram +ve diplococci
2. Gram -ve diplococci
3. Gram +ve cocci in clusters
4. Gram +ve bacilli
5. Gram -ve bacilli
- Strep pneumoniae
- Neisseria meningitidis
- Staph aureus
- Listeria monocytogenes or clostridium perfringens
- E coli/ klebsiella
Acute worsening of infx after starting ART
IRIS (immune reconstitution inflammatory syndrome)
Brain MRI + ring enhancing lesions
toxoplasmosis encephalitis
Plaques + HHV 8
Kaposi’s sarcoma
?HIV ix
HIV abs and p24 antigen
- If -ve, repeat in 12 weeks
At what CD4 count is it considered AIDS
<200 CD4
CHancroid/ haemophilus ducreyi mx
PO azithromycin
Painful genital ulcers + lymphadenopathy
Chancroid / haemophilus ducreyi
Syphilis ix
Lesion present = dark field microscopy from lesion
- If +ve: coiled spirochaete bacterium w corkscrew appearance
If no lesion = treponema serological testing <+ve in both active AND past infx>
Syphilis mx
IM benzathine benzylpenicillin
if neurosyphilis -> IV aqueous benzylpenicillin
HIV + seizures + MRI showing demyelination
Progressive multifocal leukoencephalopathy
Crypotococcal meningitis mx
Amphotericin B and Flucytosine
C diff mx
PO Vancomycin
Steatorrhoea + travel abroad
Giardia
Stool watery and then bloody - traveled to africa or asia
Shigella
Salmonella v campylobacter incubation period
Salmonella 8-72h
Campy 1-7 days
Thick v thin film for malaria ix
Thick = diagnose
Thin = subtype
Bulls eye rash (erythema chronicum migrans)
Lyme disease
Retro-orbital pain, myalgia, and rash
Dengue
Relative brady + rose spots
Salmonella typhi
Ix for infx mononucleosis (epstein barr)
monospot blood test
Malaria mx
Artemisinin combo therapy
Which malaria is severe TM
P. falciparum
