Breast Flashcards
1
Q
What hormone therapies can be given for ER positive cancers?
A
- Aromatase inhibitors (blocks production of oestrogen, typically given to postmenopausal)
- Tamoxifen (blocks effects of oestrogen on breast cells, typically given after surg)
2
Q
Fibroadenoma features
A
- Well-circumcised, solid mass
- Histology: duct-like structures lined by reg, low columnar cells & separated by loose fibrous tissue + stromal + epithelial elements
3
Q
Which drug for HER2+ve cancer?
A
Herceptin/ trastuzumab
4
Q
What neoadjuvant therapy is often used in breast ca if ER/HER2 +ve?
A
Chemo
5
Q
Which ix should be done before starting trastuzuman treatment?
A
ECHO due to SE profile of cardiomyopathy
6
Q
DCIS mx
A
If localised and lower grade
- Excision + neoadjuvant radiotherapy
7
Q
Biopsy which suggests incr risk for subsequent development of breast carcinoma
A
atypical ductal hyperplasia
