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things i don't know, but need to know, for fourth year > Oncology > Flashcards

Oncology Flashcards

1
Q

What is the characteristic finding of Dry Macular Degeneration?

A

Drusen

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2
Q

What is found in wet AMDR

A

Choroidal Neovascularisation

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3
Q

Whats the first line investigation in AMDR

A

Slitlamp

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4
Q

In wet AMDR what investigation is often used?

A

Flourescein Angiography

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5
Q

What is seen in Grade 1 Hypertensive Retinopathy?

A

Tortuous Arteries and Increased light reflex

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6
Q

What is seen in grade 2 hypertensive retinopathy?

A

Arterial Nipping

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7
Q

What is seen in grade 3 hypertensive retinopathy?

A

Cotton Wool Spots
Exudates
Falme Blot Haemorhages

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8
Q

What is seen in grade 4 Hypertensive retinopathy

A

Papilloedema

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9
Q

AFP

A

Hepatocellular carcinoma

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10
Q

CA 19-9

A

Pancreatic and billiary tree

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11
Q

CA15-3

A

Breast cancer

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12
Q

CA - 125

A

Ovarian

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13
Q

Flushing Diarrhoea Tachychadia Bronchospams Hypotension

Raised 5HIAA

A

Carcinoid syndrome - neuroendocrine tumour. Symptoms develop when metastasise to the Liver or less commonly the lungs

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14
Q

In carcinoid syndrome what medication can be used?

A

Somatostatin analogue - ocreotide.

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15
Q

What malignancy is acanthoma nigricans related to and where is it likely to present?

A

Gastric Adenocarcinoma

Up to 50% present on the tongue

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16
Q

What is used to control pain related to bony metastases?

A

Opiods
Bisphosphonates
Radiotherapy

17
Q

Chemotherapy Agent that is neurotoxic

A

Asparganine

18
Q

Chemotherapy Agent that is Fibrotic

A

Bleomycin

19
Q

Chemotherapy Agent that is renal and ototoxic

A

Cisplatin

20
Q

Chemotherapy Agent that is cardiotoxic

A

Doxorubicin

21
Q

Chemotherapy Agent that causes peripheral neuropathy

A

Vincristine

22
Q

Chemotherapy Agent that causes hemorrhagic cystitis and SIADH

A

Cyclophosphamide

23
Q

Chemotherapy Agent that is myelosuppresive and nephrotoxic

A

Methotrexate

24
Q

If someone undergoing Chemotherapy has a previous history of neutropenia secondary to chemo or any neutropenia what can they receive?

A

Filgrastin - Granulocyte Colony stimulating Factor

25
Q

Staging of ovarian cancer

A

Stage 1 - confined to ovary
Stage 2 - beyond ovary but confined to pelvis
Stage 3 - beyond pelvis into abdomen
Stage 4 - distant metastases

26
Q

Management of ovarian cancer

A

Stage 1/2 = Surgery = a total abdominal hysterectomy + bilateral salpingo-oophorectomy + infracolic omentectomy + biopsies of any peritoneal deposits + retroperitoneal lymph node assessment
- offer chemotherapy if suboptimal surgery completed
Stage 3+ = Surgery + chemotherapy
- chemotherapy is generally 6 cycles of carboplatin

27
Q

Suspecting malignant spinal chord compression

A

Full spine MRI + oral dexamethasone

28
Q

Ovarian tumours commonly spread to which lymph nodes?

A

Para aortic

29
Q

Uterine fundus tumours commonly spread to which lymph nodes?

A

Para aortic

30
Q

Uterine body tumours commonly spread to which lymph nodes?

A

Iliac lymph nodes

31
Q

Cervical cancers commonly metastasis to which lymph nodes?

A

External iliac
Presacral nodes
Internal iliac nodes

32
Q

If given pre chemotherapy what medication can help reduce the likelihood of developing tumour lysis syndrome?

A

Allopurinol

33
Q

What chemotherapy drug can precipitate hypo magnesia?

A

Cyclophophamide

34
Q

Meigs syndrome

A

Benign ovarian tumour, Ascites and pleural effusion

35
Q

Management of meigs syndrome

A

Surgical removal of tumour usually resolves symptoms

May require drainage of ascites or effusion

36
Q

Which hormone therapy used in breast cancer is cardio toxic

A

Trastuzumab

37
Q

Absent red reflex
Strabismus
Visual impairment
Usually a child

A

Retinoblastoma
AD inherited in 10%
>90% survive to adulthood

38
Q

Management of a retinal blastoma

A

Enucleation

External Beam radiotherapy

39
Q

Nuclei are.
Enlarged
Hyperchromic
Pleomorphic

A

Carcinoma

things i don't know, but need to know, for fourth year (31 decks)

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