Genetics Flashcards
1
Q
What are the rules surrounding mitochondrial inheritance
A
Affected males cant pass on the condition
Affected females will pass on to all children
All who inherit it will get it
2
Q
Prader Willi inheritance
A
Genomic Imprinting - phenotype depends on which parent it is inherited from
3
Q
If a female has developed an X linked condition what has happened?
A
The patient must have only one X chromosome i.e Turners 45XO
4
Q
Fragile X is associated with what cardiac abnormality
A
Mitral valve prolapse
5
Q
Inheritance of both Beckers and Duchennes muscular dystrophy.
A
X linked
Beckers is less severe - onset after 10 years old
6
Q
How is Charcot Marie Tooth type 1 inherited?
A
Autosomal Dominant
7
Q
What mode of inheritance do all haemophilias have?
A
X linked recessive
