Olanzapine

Question 1

Pharmacology and presentation of Olanzapine?

Answer 1

5mg wafers

-Atypical antipsychotic with actions at multiple receptors within the brain causing a reduction in agitation, sedation, anxiolysis and mood stabilisation

Question 2

Indicators of Olanzapine?

Answer 2

• Patients aged greater than or equal to 12 years with agitated delirium causing a mild to moderate risk to safety, when the patient will take an oral medicine

Question 3

Contraindications of Olanzapine?

Answer 3

• Known severe allergy.
• Poisoning with an antipsychotic, for example quetiapine or risperidone.

Question 4

Cautions of Olanzapine?
PIE

Answer 4

• Pregnancy.
• Intoxication.
• Elderly and/or frail.

Question 5

Side Effects of Olanzapine?

Answer 5

• Sedation

Question 6

Dosing Regimes of Olanzapine?

Answer 6

• 10 mg PO.
• Reduce the patient to 5 mg PO if the patient is frail.
• The dose may be repeated once after 20 minutes

Question 7

Onset and duration of Olanzapine?

Answer 7

Onset:
- 10-20mins

Duration
- 12-24hrs