Droperidol

Question 1

Pharmacology and presentation of Droperidol?

Answer 1

10mg in 2ml

• Sedative that blocks central dopamine and alpha receptors resulting in mental detachment and decreased agitation

Question 2

Indicators of Droperidol?

Answer 2

• Patients aged greater than or equal to 12 years with agitated delirium causing a mild to moderate risk to safety, when olanzapine has not been administered or is ineffective.

Question 3

Contraindications of Droperidol?

Answer 3

• Known severe allergy

Question 4

Cautions of Droperidol?
(PIES)

Answer 4

• Parkinson’s disease. Worsens movement
• Intoxication.
• Elderly and/or frail.
• Concurrent administration of other sedatives.

Question 5

Side Effects of Droperidol?

Answer 5

• Hypotension, generally due to rapid IV administration

Question 6

Dosing Regimes of Droperidol?

Answer 6

10mg lM or lV.
- Reduce the dose to 5 mg if the patient is frail.
- The initial dose may be repeated once after 20 minutes.

Question 7

Onset and duration of Droperidol?

Answer 7

Onset:
- 5-10 minutes

Duration
- 4-6 hours