Oesophageal Flashcards

1
Q

Plummer Vinson syndrome

A

Oesophageal webs.

Angular stomatitis

Glossitis

Fe Defiecency

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2
Q

What type of oesophageal cancer do western people get?

A

Usually adenocarcinoma (A for Americans)
Developss a result of Barrett’s.
Smoking and alcohol

Progressive dysphagia, solids then liquids.

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3
Q

What prompts an urgent referral?

A

New onset dysphagia and > 55.

Age > 55 with upper abdo pain, reflux or dyspepsia.

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4
Q

How do you diagnose oesophageal cancer?

A

OGD and biopsy,

Staging = CT CAP

Lymph nodes - PET CT.

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5
Q

How does achalasia present?

A

Birds beak appearance on barium swallow

Incomplete relaxation of LOS on manometry.

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6
Q

1st line investigation of dysphagia?

A

OGD.

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7
Q

Management of achalasia?

A

Muscle relaxants (CCB or nitrates)

Definitive = Heller’s cardiomyotomy (need lifelong PPI after procedure)

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8
Q

How does diffuse oesophageal spasm present?

A

Intermittent dysphagia +/- retrosternal pain.

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9
Q

How does diffuse oesophageal spasm present on Barium swallow?

A

Corkscrew appearance.

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10
Q

What would make you suspect eosinophilia oesophagitis?

A

Young male patient with personal or family history of atopy and GORD like symptoms.

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11
Q

Appearance of eosinophillic oesophagitis on OGD?

A

Schatsi’s rings, mucosa has a corrugated appearance.

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12
Q

When would you refer for GORD?

A

If >55years >4weeks duration, weight loss, dysphagia or persistent symptoms despite Rx.

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13
Q

What is a starting dose of a PPI?

A

20mg OD

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14
Q

What are PPIs contraindicated in?

A

Osteoporosis.

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15
Q

Side effect of PPI?

A

Hyponatraemia.

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16
Q

What is an example of a H2 antagonist?

A

Ranitidine.

17
Q

How does ondansteron work?

A

5-HT3 receptor antagonists (serotonin)

18
Q

How does cylizine work?

A

H1 receptor antagonists (anti-histamine)

19
Q

How does domperidone/prochlorepazine work?

A

Domperidone is a peripheral D2 and D3 dopamine receptor antagonist.

20
Q

What is the change in barrels oesophagus?

A

Stratified squamous epithelium to glandular columnar.