Crohns

Question 1

What is Crohn’s disease?

Answer 1

Inflammatory condition that can affect anywhere from the mouth to the anus.

Question 2

Where does the inflammation most commonly affect?

Answer 2

The terminal ileum.

Question 3

Is smoking good or bad for crohns

Answer 3

Smoking is bad for Crohn’s disease.

Question 4

Main histological findings of crohns?

Answer 4

Non-caseating granulomas
Deep inflammation that gives the bowel a cobblestone appearance.
Skip lesions.

Question 5

If terminal ileum is affected, what can occur?

Answer 5

Malabsorption of B12 thereforewe a macocytic anaemia,.

Question 6

Presentation of crohns?

Answer 6

Diarrhoea
Abdo pain
Peri anal disease (skin tags, fistula, anal or rectal strictures)

Question 7

Investigation of crohns?

Answer 7

Assessing full extent = colonscpy.

Question 8

Treatment ?

Answer 8

1) Corticosteroid (Prednisolone)
2) Immunisupperession (azathiprine, sulfasalsine, methotrexate)
3) anti TNF (infliximab)

Non curative surgery