Liver function tests / Liver disease

Question 1

ALT > AST?

Answer 1

Chronic liver disease

Question 2

AST > ALT ?

Answer 2

Alcoholic liver disease?

Question 3

Which one is specific to the liver?A

Answer 3

ALT

Question 4

Where is ALP found?

Answer 4

Biliary ducts, bones, and placenta.

Question 5

What is GGT used for?

Answer 5

To confirm that ALP is hepatic in nature or to monitor alcoholic liver disease.

Question 6

What LFT gives the best immediated measure of functional liver capacity?

Answer 6

Coag.

Question 7

Pattern seen of coag in acute liver disease?

Answer 7

Increased pro-thrombin time/INR.

Question 8

Low albumin high protein suggest what?

Answer 8

Myeloma.

Question 9

WHat auto-antibodies in primary biliary cirrhosis?

Answer 9

Anti-mitochondrial

Increased IgM.

Question 10

What auto-antibodies in PSC?

Answer 10

• Anti smooth muscle

- P-ANCA (Stu T IS A WANKA)

Question 11

Auto-antibodies in autoimmune hepatitis/

Answer 11

Anti smooth msycke.

Anti liver kidney micrsomal, increased IgG

Question 12

1st line test for Hep A?

Answer 12

IgM = acute infection

IgG = Chronic infection

Question 13

How is hep A spread?

Answer 13

Faecal oral.

Question 14

How is Hep C spread?

Answer 14

Unprotected sex or needle sharing.

Question 15

Test for acute Hep C?

Answer 15

Hep C RNA PCR

\+ve = current infection 
-ve = past infection

Question 16

Treatment of Hep C

Answer 16

Peg interferin + Ribavarain.