odontogenesis Flashcards
odontogenesis
2) bud stage
3) cap stage
4) bell stage
–
5) crown/maturation stage
timeline of development
1) 42-48 days
- dental lamina formation
2) 55-56 days
- bud stage of deciduous incisors, canines, molars
3) 14 weeks
- bell stage for deciduous, bud for permanent
4) 18 weeks
- dentin and functional ameloblasts in deciduous teeth
5) 32 week
- dentin and functional ameloblasts in permanent teeth
initiation stage
1) formation of a continuous horseshoe shaped band of thickened epithelium
- stratified squamous
2) primary oral epithelium / primary epithelial band
3) each band of epithelium give rise to the dental lamina
4) dental placode inside DL
- initiation knot - transient signaling center
- primary oral epithelium presents odontogenic potential
bud stage
1) dental lamina grows into the ectomesenchyme
2) tooth bud formed by epithelial cells
3) condensation of ectomesenchymal cells around the epithelial bud
- now assumes odontogenic potential
early cap stage
1) the enamel organ
- outer enamel epithelium (glycogen)
- inner enamel epithelium (glycogen)
-stellate reticulum (glycosaminoglycans)
2) dental papilla and dental follicle
3) inner enamel epithelium
- ameloblasts
4) dental papilla
- dental pulp and odontoblasts
5) dental follicle
- cementoblasts, PDL, and alveolar bone proper
—
this is called the “tooth germ”
- enamel organ, dental papilla, dental follicle
advanced cap stage
1) formation of enamel knot
- clusters of nondividing epithelial cells
- signaling and pattern formation of cusps
2) signal center that represents a organizational center which orchestrates cuspal morphogenesis
cap to bell stage
1) primary enamel knot disappears and secondary enamel knots form
- at future locations of the cusps in premolars and molars
2) it is a signaling center
bell stage
1) shape of the crown is established
2) the enamel knot disappears
2) formation of stratum intermedium
4) dental lamina begins to break up into discrete islands of epithelial cells (of serres)
5) formation of cervical loop
- root formation
6) mineralization starts
- amelogenesis (ameloblasts)
- dentinogenesis (odontoblasts)
bell stage formation of permanent tooth
1) successional lamina arises from the dental lamina of the deciduous teeth (incisors, canines, and pre-molars)
crown and maturation stage
1) increase minerals
2) increase size
3) maturation of crystals
4) completion of the crow formation
how is tooth type determined
1) field model
2) tooth family
field model genetic factors
1) presumptive incisor mesenchyme
- Msx-1, Msx-2, Alx-3
2) presumptive canines and premolar region
- Dlx1/2, Msx-1
3) presumptive molar region
- barx-1 and dlx-1/2
anodontia (partial or complete)
1) absence of permanent or primary teeth that commonly include permanent third molar, maxillary lateral incisors, or second premolar
2) hereditary, endocrine, systemic disease, excess radiation that prevents tooth germ formation
supernumerary tooth
1) development of one or more extra teeth that are commonly found between the permanent maxillary central incisors (mesiodens) distal to third molars, and premolar region
2) hereditary with extra tooth germ formation from persisting dental lamina clusters