obstetrics Flashcards
pelvis uterus a t what age of pregnancy
12 weeks
cardiovascular changes in pregnancy(4)
Increase cardiac output
increase haert rate
increase stroke volume
decrease BP
systolic murmur and S3 during pregnancy
normal
diastolic murmur in pregnancy
abnormal
thyroid hormone in pregnancy
high total and bound T3 T4
role of HPL human placental lactogen
acts as insulin antagonist to maintain fetal glucose levels
why acid reflux during pregnancy
decrease gastro esophageal sphincter tone
why constipation in pregnancy(2)
decrease large bowel motility
increase water reabsorbtion
why pregnant women are prne to gallstones
because of high biliary cholesterol saruration
anemia in pregnant women
because of increase plasma volume
wbc in pregnant women
10,5 million
leading nonobstetric cause of postpartum death
thromboembolic disease
hb < 11 in pregnant woman
it’s pathologic
respiratory in pregnant women(2)
high alveolar and arterial P02
decrease alveolar and arterial PCO2
kidney function in pregnancy(2)
dilation of the collecting system
high GFR
Skin changes in pregnancy (3)
spider angiomas
palmar erythema
hyperigmentation
quid of chloasma in pregnancy
hyperpigmentation of the face
diastasis recti in pregnancy
separation of rectus muscles in the midline
weight gain during pregnancy
25 a 35 lbs
kilocalorie needed /day
300 kcal/day
supplement during pregnancy
1 mg acide folique
iron 30- 60 mg par jour
importance of folic acid
to prevent neural tube problem
Nagele’s rule or due date
last menstrual period+nine months +seven days
MAternal alpha feto protein date pour screenMSAF
15-20 weeks
who produce alpha feoto protein
baby
quid of High AFP
> 2,5 MoMs
cause of high AFP(6)
neural tube defects abdominal wall dec=fect multiple gestation fetal death incorrect gestationnal dating placental abnormalities
quid of abdominal wall defect(2)
gastrochisis
omphalocel
quid of neural tube defect(2)
spina bifida
anencephaly
low AFP
< 0,5 Mom
next step denvant low AFP
rule out chromosomal abnormalities
role of triple screen
to detect chromosomal abnormalities
elements in triple screen(3)
Bhcg
estriol
MSAF
triple screen high
trisosmie 18
triple screen in down
low AFP
low estriol
high BHCG
best test to detect trisomies
triple test
indication of amniocentesis(2)
> 35 ans et grossesse
to evaluate lung maturity
mature lung
lecithin/sphingomyeline> ou egal 2,5
time to perform amniocentesis
15 -17 semaines
risk in amniocentesis(2)
maternal hemorrage
fetal loss
disavantages of chorionic villus sampling(2)
1% risk of fetal loss
inability to dx neural tube defects
latent phase of labor
entre 3 et 4 cm
first stage of labor(2)
latent
active
active labor
4 cm to complet dilation
duration of latent phase in primi
6-11 h
duration of latent phase in multi
4-8 hrs
duration of active phase in primi(2)
4-6 h
1,2 cm par heure
duration of active phase in multi(2)
2-3 hres
1.5 cm par heure
prolongation of active phase
cephalopelvic disproportion
second phase of labor
complete dilation to delivery of baby
second phase in primi duration
0,5 a 3 h
second phase in multi duration
5 a 30 mn
third phase
from delivery of infant to delivery of the placenta
third phase in primi and Multi
0-0,5 h
profil biophysique Test the Baby MAN
Tone fetal Breathing fetal Movement fetal Aminiotic fluid Nonstress test
hyperglycemia in the first trimester quid of that
diabete in Mom
Dx of gestationnal diabetes
fasting serum glucose>126 mg/dl
random glucose> 200
abnormal glucose challenge test> 140
when perform screening for gestationnal diabetes
24 -28 semaines
test routinely used to screen gestationnal diabetes
glucose challenge test
next step if glucose challenge test is > 140(confirmation)
3 hour glucose tolerance test
value to confirm gestationnal diabetes in 3 hour glucose tolerance test(4)
fasting > 95
one hour>180
2 hours> 155
3 hours> 140
maternal complication of diabete type 2(8)
DKA (type 1) or HHNK (type 2) Macrosomia Preeclampsia/eclampsia Cephalopelvic disproportion Preterm labor Infection Polyhydramnios Postpartum hemorrhage Maternal mortality
fetal complication of gestationnal diabetes(11)
Macrosomia Cardiac and renal defects Neural tube defects (e.g., sacral agenesis) hypocalcemia Polycythemia Hyperbilirubinemia Intrauterine growth restriction (IUGR) Hypoglycemia from hyperinsulinemia Respiratory distress syndrome (RDS) Birth injury (e.g., shoulder dystocia) Perinatal mortality
Gestational hypertension quid
idiopathic hypertension without significant proteinuria (< 300
mg/L)
when gestationnal hTA begins(3)
second half of pregnancy,
during labor, or
within 48 hours of delivery
can a patietn patient with gestationnal HTA develops preecclampsia
yes
Chronic hypertension(2)
before conception and at < 20 weeks of gestation
or may persist for > 12 weeks postpartum
effect negatif of ACE I on mother
uterine ischemia
quid of oligoamnios
amniotic fluid index
(AFI) < 5 on ultrasound
etiologies of oligoamnios(3)
fetal urinary tract abnormalities
chronic uteroplacental insufficiency
ROM
urinary tract abnormalities assocciated with oligoamnios(3)
renal agenesis,
polycystic kidney disease,
GU obstruction
categorisation of preecclampsia
Mild
severe
Mild precclampsia
BP > 140/90 on two occasions
> 6 hours apart
proteinuria in mild precclampsia
Proteinuria > 300 mg/24 hrs
severe precclampsia
BP > 160/110 on two occasions > 6 hours apart
proteinuria in severe preecclampsia
Proteinuria > 5 g/24 hrs
alcool teratogenicity
fetal alcohol syndrome
quid of fetal alcohol syndrome(5)
microcephaly, midfacial hypoplasia, mental retardation, IUGR, cardiac defect
Cocaine teratogenicity(3)
Bowel atresias,(jejunal)
IUGR,
microcephaly
Streptomycin teratogenicity(2)
CN VIII damage/
ototoxicity
Tetracycline teratogenicity(4)
Tooth discoloration,
inhibition of bone growth,
small limbs,
syndactyly.
Sulfonamides teratogenicity
Kernicterus.
Quinolones teratogenicity
Quinolones Cartilage damage.
Isotretinoin teratogenicity(4)
Isotretinoin Heart and
great vessel defects,
craniofacial dysmorphism,
deafness.
Iodide teratogenicity(3)
Congenital goiter,
hypothyroidism,
mental retardation.
Methotrexate teratogenicity(3)
\CNS malformations,
craniofacial dysmorphism,
IUGR.
DES teratogenicity(3)
Clear cell adenocarcinoma of the vagina/cervix,
genital tract abnormalities
cervical incompetence.
genital tract abnormalities of DES(3)
cervical hood,
T-shaped uterus
hypoplastic uterus
Thalidomide teratogenicity(5)
Limb reduction (phocomelia), ear and nasal anomalies, cardiac and lung defects, pyloric or duodenal stenosis, GI atresia.
Coumadin teratogenicity(4)
Stippling of bone epiphyses,
IUGR,
nasal hypoplasia,
mental retardation.
ACEIs teratogenicity(2)
Oligohydramnios,
fetal renal damage.
Lithium teratogenicity(2)
Ebstein’s anomaly,
other cardiac diseases.
Carbamazepine teratogenicity(4)
Fingernail hypoplasia,
IUGR,
microcephaly,
neural tube defects
Phenytoin teratogenicity(5)
Nail hypoplasia, IUGR, mental retardation, craniofacial dysmorphism, microcephaly
Valproic acid teratogenicity(3)
Neural tube defects,
craniofacial and
skeletal defects.
quid of polyhydramnios
AFI > 20
etiologies of polihydramnios(6)
maternal DM, multiple gestation, isoimmunization, pulmonary abnormalities twintwin transfusion syndrome. fetal anomalies
fetal anomalies causing poplihydramnios(3)
duodenal atresia,
tracheoesophageal fistula,
anencephaly
pulmonary abnormalities causing polyhydramnios
cystic lung malformation
4 parameters to consider in intrauterine growth restriction
Biparietal diameter
Head circumference
Abdominal circumference
Femur length
symmetric growth restriction
all for parameters are affected
asymmetric growth restriction
only abdominal circumference is decreased
time of insult in symmetric growth restriction
early in pregnancy
time insult in asymmetric growth restriction
late in pregnancy
etiology in symmetric growth restriction
fetal problem
fetal problem causing symmetric growth restriction(3)
Cytogenetic
Infection
Anomalie
etiology in asymmetric growth restriction
Placenta mediated:
placental problem causing asymmetric growth restriction(3)
Hypertension
Poor nutrition
Maternal smoking
preecclampsia in the first trimester
mole hydatiforme
genotype of complete mole
46XX
genotype of incomplete mole
69XXY
particcularity of incomplete mole
contain fetal tissue
clue for mole hydatiform(4)
first-trimester uterine bleeding (most common), hyperemesis gravidarum,
preeclampsia/eclampsia at < 24 weeks,
uterine size greater than dates
ultrasound of mole hydatiform(complete)
snowstorm
what to avoid during mole hydatiform
preventbpregnancy for one year
quid of mole hydatiform
fertilization of an empty ovum
quid of third trimester bleeding
after 20 weeks
most common cause of 3 trimester bleeding(2)
Preavia
abruptio placentae
3 types of preavia
Total: Placenta covers cervical os.
Marginal: Placenta extends to margin of os.
Low-lying: Placenta in close proximity to os.
Total praevia
Placenta covers cervical os
Marginal praevia
Placenta extends to margin of os.
Low-lying praevia
Placenta in close proximity to os.
C-section indication in placenta praevia(5)
persistent labor, life-threatening bleeding fetal distress, documented fetal lung maturity, 36 weeks’ GA.
complications of abruptio
hemorragic shock
DIC
fetal hypoxia
Recurrence risk is 5–16%
probability for having abruptio after 2 episode of abruptio
25%
complication of placenta previa(7)
risk of placenta accreta. Vasa previa premature rupture of membranes preterm delivery IUGR congenital anomalies. Recurrence risk is 4–8%.
the most common fetal malpresentation
breech presentation
3 types of breech
Frank breech (50–75%):
■ Footling breech (20%):
■ Complete breech (5–10%): Thighs and knees are flexed.
frank breech
Thighs are flexed and knees are extended.
footling breech
One or both legs are extended below the buttocks.
Complete breech
Thighs and knees are flexed.
failure to progress in prima in latent phase
> 20 h
failure to progress in multi in latent phase
> 14 h
failure to progress in active phase
Active Failure to have progressive cervical change
after reaching 3–4 cm.
arrest of fetal descent in primi
> 3 h
arrest of fetal descent in multi
> 2 h
post partum hemorrage
> 500 mL of blood for vaginal delivery or
> 1000 mL after C section
Maternal factors for C section(4)
Prior classical C-section
Active genital herpes infection
Cervical carcinoma
Maternal trauma/demise
most common cause of C section
CPD
fetal and maternal factors for C swection(5)
Cephalopelvic disproportion Placenta previa/ placental abruption Failed operative vaginal delivery post date pregnancy(relative)
fetal factors for C section(4)
fetal malposition
fetal distress
cord compression
erytroblastose fetalis
fetal malposition for c section(3)
posterior chin
transverse lie
shoulder presentation
post partum infection
≥ 38°C for at least two of the
first ten postpartum days (not including the first 24 hours)
most common cause of post partum hemorrage
uterine atony
3 causes of post partum hemorrage
UTERINE ATONY
GENITAL TRACT TRAUMA
RETAINED PLACENTAL TISSUe
causes of uterine atony(4)
Uterine overdistention Exhausted myometrium Uterine infection. Conditions interfering with contractions
cause of uterine over distension(3)
macrosomie
multiple gestation
polyhydramnios
causes of exhausted myometrium(2)
prolonged labor
oxytocin stimulation
Conditions interfering with
contractions(3)
anesthesia,
myomas,
MgSO4
genital tract trauma causing post partum bleeding
Inadequate episiotomy repair.
Large infant.
Operative vaginal delivery
Precipitous labor
quid of operative vaginal delivery(2)
vacuum
forceps
cause retained placental tissue(5)
Previous C-section/curettage. Preterm delivery. Uterine leiomyomas. Placenta previa Placenta accreta/increta/percreta
rx of uterine atony(4)
uterine massage
oxytocin
methergin
prostin(PGF 2@)
cause of post partum fever 7 w
Womb (endomyometritis) Wind (atelectasis, pneumonia) Water (UTI) Walk (DVT, pulmonary embolism) Wound (incision, episiotomy) Weaning (breast engorgement, abscess, mastitis) Wonder drugs (drug fever
rx of mastitis(2)
antibio
continue breasfeeding
complete abortion
all POC are expelled
OS is closed
incomplete abortion
some POC expelled
OS is open
threatened abortion(2)
No POC expelled
OS is closed
nevitable abortion(3)
bleeding
No POC expelled
OS is open
Missed abortion(3)
No POC expelled
Pregnancy has ceased to develop
Os is closed
quid of reccurent abortion
> ou egal a 2 consecutives spontaneous abortions
what to evaluate in reccurent abortion(2)
karyotyping of both parents
incompetent cervix