Obligate Intracellulars Flashcards
What cells are the target of Rickettsia?
ENDOTHELIAL cells –> capillary thrombi form, hemorrhage
2 Diseases caused by Rickettsia
- Typhus in humans (R. prowazekii)
- Rocky Mountain Spotted Fever (R. rickettsia and parkeri)
Typhus vector?
louse
Rickettsia vector?
tick
What is the most prevalent tick-borne livestock pathogen?
Anaplasma marginale
How to diagnose anaplasmosis?
cytology –> Giemsa and IFA
2 Pathogens that cause Canine Anaplasmosis and the difference?
- Anaplasma phagocytophilum (infects neutrophils)
- Anaplasma platys (infects blood platelets)
Target of A. marginale?
RBCs (livestock)
Target of A. phagocytophilum?
neutrophils (canine)
Potomac Horse Fever Pathogen
Neorickettsia risticii
How do horses get Potomac Horse Fever?
ingestion of snails containing trematode stages of N. risticii
Canine Salmon Poisoning Pathogen
Neorickettsia helminthoeca
How do dogs get salmon posioning?
they eat fish that have eaten snails with the trematode that carries N. helminthoeca
Cytologic Appearance of Chlamydia
intracytoplasmic inclusions are draped around the infected cell nucleus
Infectious Life Cycle of Chlamydia?
elementary bodies
What is unique about the cell wall of chlamydia?
NO peptidoglycan - made of cysteine-rich proteins
Virulence Mechanism of Chlamydia
attach to sialic acid receptors in eye, throat, or genitalia
Chlamydia psittaci
parrots, parakeets, turkeys with eyes pasted shut with exudates
Is psittacosis zoonotic?
yes, birds can infect their humans
Bartonella henselae
Pathogen of cat scratch disease
Infectious Bovine Keratoconjunctivitis pathogen?
Moraxella bovis
Infectious Bovine Keratoconjunctivitis (IBK) (pinkeye) is induced by what?
solar radiation
IBK symptoms
tear production, avoidance of sunlight, progressing to cloudy/white, ulcerated, lose lens and vision
Does M. bovis spread from calf to dam?
no
