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607 Bacteriology > Obligate Intracellulars > Flashcards

Obligate Intracellulars Flashcards

1
Q

What cells are the target of Rickettsia?

A

ENDOTHELIAL cells –> capillary thrombi form, hemorrhage

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2
Q

2 Diseases caused by Rickettsia

A
  1. Typhus in humans (R. prowazekii)
  2. Rocky Mountain Spotted Fever (R. rickettsia and parkeri)
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3
Q

Typhus vector?

A

louse

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4
Q

Rickettsia vector?

A

tick

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5
Q

What is the most prevalent tick-borne livestock pathogen?

A

Anaplasma marginale

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6
Q

How to diagnose anaplasmosis?

A

cytology –> Giemsa and IFA

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7
Q

2 Pathogens that cause Canine Anaplasmosis and the difference?

A
  1. Anaplasma phagocytophilum (infects neutrophils)
  2. Anaplasma platys (infects blood platelets)
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8
Q

Target of A. marginale?

A

RBCs (livestock)

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9
Q

Target of A. phagocytophilum?

A

neutrophils (canine)

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10
Q

Potomac Horse Fever Pathogen

A

Neorickettsia risticii

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11
Q

How do horses get Potomac Horse Fever?

A

ingestion of snails containing trematode stages of N. risticii

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12
Q

Canine Salmon Poisoning Pathogen

A

Neorickettsia helminthoeca

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13
Q

How do dogs get salmon posioning?

A

they eat fish that have eaten snails with the trematode that carries N. helminthoeca

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14
Q

Cytologic Appearance of Chlamydia

A

intracytoplasmic inclusions are draped around the infected cell nucleus

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15
Q

Infectious Life Cycle of Chlamydia?

A

elementary bodies

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16
Q

What is unique about the cell wall of chlamydia?

A

NO peptidoglycan - made of cysteine-rich proteins

17
Q

Virulence Mechanism of Chlamydia

A

attach to sialic acid receptors in eye, throat, or genitalia

18
Q

Chlamydia psittaci

A

parrots, parakeets, turkeys with eyes pasted shut with exudates

19
Q

Is psittacosis zoonotic?

A

yes, birds can infect their humans

20
Q

Bartonella henselae

A

Pathogen of cat scratch disease

21
Q

Infectious Bovine Keratoconjunctivitis pathogen?

A

Moraxella bovis

22
Q

Infectious Bovine Keratoconjunctivitis (IBK) (pinkeye) is induced by what?

A

solar radiation

23
Q

IBK symptoms

A

tear production, avoidance of sunlight, progressing to cloudy/white, ulcerated, lose lens and vision

24
Q

Does M. bovis spread from calf to dam?

A

no

25
Q

Is there correlation between M. bovis and IBK in dam?

A

no

26
Q

Is there correlation between M. bovis and IBK in the calf?

A

yes

27
Q

Diagnosis of IBK?

A

based on ocular signs

607 Bacteriology (24 decks)

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