HAP

Question 1

Why are these grouped together?

Answer 1

RESPIRATORY INFECTIONS

Question 2

HAP are 4?

Answer 2

1. Haemophilus
2. Histophilus
3. Actinobacillus
4. Pasteurella

Question 3

Glasser’s disease

Answer 3

Haemophilus parasuis (pigs), concurrent viral infection, causes polyserositis and endothelial disruptions

Question 4

Is haemophilus commensal?

Answer 4

yeah, it chills in the respiratory tract, so usually an opportunistic secondary infection

Question 5

Histophilus somni

Answer 5

part of bovine respiratory disease complex in feedlot calves (stressed), causes somnolence

Question 6

Somnolence

Answer 6

strong desire to sleep for long period of time

Question 7

Hemotogenous spread

Answer 7

done by H. somni

bacteria adhere to endothelium of vessels, endothelial cells apoptose, leading to vasculitis, petechia, thrombi –> tissue death

Question 8

Where does Histophilus somni ALWAYS end up?

Answer 8

UTERUS

Question 9

Actinobacillus ligniersii disease?

Answer 9

Wooden tongue in adult cattle!

Question 10

Actinobacillus equuli disease?

Answer 10

sleepy foal disease (septicemia in foals)

Question 11

Actinobacillus pleuropneumonia

Answer 11

SUDDEN DEATH in pigs due to endotoxin (LPS), has rapid rate of cell division so body is quickly overwhelmed; very virulent

Question 12

Diseases caused by Pasteurella multocida (3)

Answer 12

1. Atrophic rhinitis
2. Shipping fever (BRDC)
3. Fowl cholera

Question 13

Two most common capsule types in P. multocida?

Answer 13

A and D

Question 14

Pastuerella multocida toxin (PMT)

Answer 14

works with Bordetella demonecrotic toxin (DNT) to cause atropic rhinitis

Question 15

WHAT IS THE MOST FREQUENT BACTERIAL PATHOGEN ASSOCIATED WITH SHIPPING FEVER?

Answer 15

Mannheimia haemolytica (serotype A1)

Question 16

What is unique about Biberstenia trehalosi and BRDC?

Answer 16

usually found with a BACTERIAL coinfection rather than a viral