obesity Flashcards
How is obesity determined on the bmi scale
a BMI greater than 30
BMI = weight/height ^2
What are some negative health consequences of obesity
Worse sleep, movement and mental health
increased risk of, T2 diabetes, stroke, heart or vascular issue
What is the energy balance model of obesity
E intake = E expendature + E stored
E intake = what you have eaten
E expendature = BMR + excersise
what is not expended is used as stored fuel
How can the energy balance model be used for potential treatement
Reduce energy intake - Hard to maintain reduced intake + body resets to a lower resting BMR when reduced intake
increase expendature -
- increased BMR - done through drugs which are dangerous
DNP - kills you vua hyperthermia
thyroid hormones - heart failure
BAM15 - showing signs but still in trials
alt increased muscle mass can help to burn more ATP at rest
- increased excersise
Often leads to the body signaling to increase intake afterwards - still has benifits with insulin sensitivity + muscle gains + CV health
How can apatite control lead to obesity
Brain regulates metabolisum and energy intake -
Eating high energy foods rewards the body -> more is wanted
what are the hormones which impact neural control of obesity and apatite
GLP1 from the L-cells in the GIT signal to reduce apatite when high GIT nutriance
Leptin from adipose tissue signals to stop eating - offten insensitivity in obese people
Alternative to increase -
Gherlin released from GIT to eat when GIT empty
What is the energy balance model and the carbohydrate insulin model of obesity
Energy balance model: increased high energy fuels -> stimuates brain reward path -> postivie energy balance -> increased adipose
carbohydrate insulin model: increased high carbohydrate fuels -> high insulin secretion -> low circulation of fuels -> increasing adipose stores -> positive energy balance
